Achievements
Dr. Hashimoto's (B01 Representative) paper was published in FEBS Letters.
Dr. Hashimoto's (B01 Representative) paper was published in FEBS Letters.
We found that oxidative stress due to reduced glutathione levels leads to increased Aβ42 and promoted tau pathology.
Hashim KN, Matsuba Y, Takahashi M, Kamano N, Tooyama I, Saido TC, Hashimoto S*. Neuronal glutathione depletion elevates the Aβ42/Aβ40 ratio and tau aggregation in Alzheimer's disease mice. FEBS letters 598(13) 1576-1590.
Dr. Tsukakoshi's (C01 Representative) paper was published in Talanta.
Dr. Tsukakoshi's (C01 Representative) paper was published in Talanta.
This is research on the development of a FRET-type sensing system using an aptamer that specifically binds to the antibody drug bevacizumab.
Yamada T, Tsukakoshi K, Furusho A, Sugiyama E, Mizuno H, Hayashi H, Yamano T, Kumobayashi H, Hasebe T, Ikebukuro K, Toyo'oka T, Todoroki K. Simple and fast one-step FRET assay of therapeutic mAb bevacizumab using anti-idiotype DNA aptamer for process analytical technology. Talanta. 2024 Sep 1;277:126349.
https://www.sciencedirect.com/science/article/pii/S0039914024007288?via%3Dihub