||最新-2021年|| ||2020-2016年|| ||2015年-2011年|| ||2010年-2006年|| ||2005年-2001年|| ||2000年-1996年|| ||1995年-1986年||

2020年

1. Functional Domain Order of an Anti-EGFR × Anti-CD16 Bispecific Diabody Involving NK Cell Activation
   Atsushi Kuwahara, Keisuke Nagai, Takeshi Nakanishi, Izumi Kumagai and Ryutaro Asano^*
   International Journal of Molecular Sciences (2020) 21 (23), 8914; doi.org/10.3390/ijms21238914


2. Creation of a novel DET type FAD glucose dehydrogenase harboring Escherichia coli derived cytochrome b562 as an electron transfer domain
   Takumi Yanase^†, Junko Okuda-Shimazaki^†, Kazushige Mori, Katsuhiro Kojima, Wakako Tsugawa and Koji Sode^*
   Biochemical and Biophysical Research Communications (2020) 530 (1), 82-86; doi.org/10.1016/j.bbrc.2020.06.132,
   †: Contributed equally


3. A Green Light-Regulated T7 RNA Polymerase Gene Expression System for Cyanobacteria
   Chika Shono^†, Dwi Ariyanti^†, Koichi Abe, Yuta Sakai, Ippei Sakamoto, Kaori Tsukakoshi, Koji Sode^* and Kazunori Ikebukuro^*
   Marine Biotechnology (2020) 23, 31-38; doi.org/10.1007/s10126-020-09997-w, †: Contributed equally


4. Monomeric G-Quadruplex-Based CpG Oligodeoxynucleotides as Potent Toll-Like Receptor 9 Agonists
   Anh Thi Tram Tu, Kazuaki Hoshi, Kazunori Ikebukuro, Nobutaka Hanagata and Tomohiko Yamazaki^*
   Biomacromolecules (2020) 21 (9), 3644-3657; doi.org/10.1021/acs.biomac.0c00679


5. Association behavior and control of the quality of cancer therapeutic bispecific diabodies expressed in Escherichia coli
   Hikaru Nakazawa, Tomoko Onodera-Sugano, Aruto Sugiyama, Yoshikazu Tanaka, Takamitsu Hattori, Teppei Niide, Hiromi Ogata, Ryutaro Asano, Izumi Kumagai and Mitsuo Umetsu^*
   Biochemical Engineering Journal (2020) 160, 107636; doi.org/10.1016/j.bej.2020.107636


6. Application of a Glucose Dehydrogenase-Fused with Zinc Finger Protein to Label DNA Aptamers for the Electrochemical Detection of VEGF
   Jinhee Lee^†, Atsuro Tatsumi^†, Kaori Tsukakoshi^†, Ellie D. Wilson, Koichi Abe, Koji Sode and Kazunori Ikebukuro^*
   Sensors (2020) 20 (14), 3878; doi.org/10.3390/s20143878, †: Contributed equally


7. Review:
   Alteration of Electron Acceptor Preferences in the Oxidative Half-Reaction of Flavin-Dependent Oxidases and Dehydrogenases
   Kentaro Hiraka, Wakako Tsugawa and Koji Sode^*
   International Journal of Molecular Sciences (2020) 21 (11), 3797; doi.org/10.3390/ijms21113797


8. Build-up functionalization of anti-EGFR × anti-CD3 bispecific diabodies by integrating high-affinity mutants and functional molecular formats
   Ryutaro Asano^*, Katsuhiro Hosokawa, Shintaro Taki, Shota Konno, Ippei Shimomura, Hiromi Ogata, Mai Okada, Kyoko Arai, Masayoshi Onitsuka, Takeshi Omasa, Takeshi Nakanishi, Mitsuo Umetsu and Izumi Kumagai^*
   Scientific Reports (2020) 10, 4913; doi.org/10.1038/s41598-020-61840-3


9. Employment of 1-Methoxy-5-Ethyl Phenazinium Ethyl Sulfate as a Stable Electron Mediator in Flavin Oxidoreductases-Based Sensors
   Maya Fitriana, Noya Loew, Arief Budi Witarto, Kazunori Ikebukuro, Koji Sode^* and Wakako Tsugawa^*
   Sensors (2020) 20 (10), 2825; doi.org/10.3390/s20102825


10. Review:
    Engineering of riboregulators for gene regulation as a tool for synthetic biology
    Kinuko Ueno, Kaori Tsukakoshi and Kazunori Ikebukuro^*
    Advances in Synthetic Biology (2020) , 173–186; doi.org/10.1007/978-981-15-0081-7_10


11. Rational engineering of Aerococcus viridans l-lactate oxidase for the mediator modification to achieve quasi-direct electron transfer type lactate sensor
    Kentaro Hiraka, Katsuhiro Kojima, Wakako Tsugawa, Ryutaro Asano, Kazunori Ikebukuro and Koji Sode^*
    Biosensors and Bioelectronics (2020) 151, 111974; doi.org/10.1016/j.bios.2019.111974


12. Construction of a circularly connected VHH bispecific antibody (cyclobody) for the desirable positioning of antigen-binding sites
    Saki Hemmi, Ryutaro Asano, Kouki Kimura, Mitsuo Umetsu, Takeshi Nakanishi, Izumi Kumagai and Koki Makabe^*
    Biochemical and Biophysical Research Communications (2020) 523, 72-77; doi.org/10.1016/j.bbrc.2019.12.018


13. Engineered Glucose Oxidase Capable of Quasi-Direct Electron Transfer after a Quick-and-Easy Modification with a Mediator
    Nanami Suzuki^†, Jinhee Lee^†, Noya Loew, Yuka Takahashi-Inose, Junko Okuda-Shimazaki, Katsuhiro Kojima, Kazushige Mori, Wakako Tsugawa and Koji Sode^*
    International Journal of Molecular Sciences (2020) 21 (3), 1137; doi.org/10.3390/ijms21031137, †: Contributed equally


14. Ethanol Detection at the Parts per Billion Level with Single‐Stranded‐DNA‐Modified Graphene Field‐Effect Transistors
    Ryo Nozaki, Takashi Ikuta, Kinuko Ueno, Kaori Tsukakoshi, Kazunori Ikebukuro and Kenzo Maehashi
    Physica Status Solidi B-Basic Solid State Physics (2020) 257 (2); doi.org/10.1002/pssb.201900376


15. Chemically Crosslinked Bispecific Antibodies for Cancer Therapy: Breaking from the Structural Restrictions of the Genetic Fusion Approach
    Asami Ueda, Mitsuo Umetsu^*, Takeshi Nakanishi, Kentaro Hashikami, Hikaru Nakazawa, Shuhei Hattori, Ryutaro Asano and Izumi Kumagai^*
    International Journal of Molecular Sciences (2020) 21 (3), 711; doi.org/10.3390/ijms21030711



2019年

1. Application of an engineered chromatic acclimation sensor for red-light-regulated gene expression in cyanobacteria
   Shunichi Kobayashi, Mitsuharu Nakajima, Ryutaro Asano, Eunice A. Ferreira, Koichi Abe, Paula Tamagnini, Shota Atsumi and Koji Sode^*
   Algal Research (2019) 44, 101691; doi.org/10.1016/j.algal.2019.101691


2. X-ray structure of the direct electron transfer-type FAD glucose dehydrogenase catalytic subunit complexed with a hitchhiker protein
   Hiromi Yoshida, Katsuhiro Kojima, Masaki Shiota, Keiichi Yoshimatsu, Tomohiko Yamazaki, Sterano Ferri, Wakako Tsugawa, Shigehiro Kamitori and Koji Sode^*
   Acta Crystallographica Section D (2019) 75 (9), 841-851; doi.org/10.1107/S2059798319010878


3. G-Quadruplex Structure Improves the Immunostimulatory Effects of Cytosine-Phosphate-Guanine Oligonucleotides
   Kazuaki Hoshi, Tomohiko Yamazaki^*, Yuuki Sugiyama, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode and Kazunori Ikebukuro
   Nucleic Acid Therapeutics (2019) 29 (4), 224-229; doi.org/10.1089/nat.2018.0761


4. Generation of C5-desoxy analogs of tetrahydroisoquinoline alkaloids exhibiting potent DNA alkylating ability
   Ryo Tanifuji, Kaori Tsukakoshi, Kazunori Ikebukuro, Hideaki Oikawa and Hiroki Oguri^*
   Bioorganic & Medicinal Chemistry Letters (2019) 29 (14), 1807-1811; doi.org/10.1016/j.bmcl.2019.05.009


5. Model studies for isolation of G-quadruplex-forming DNA sequences through a pull-down strategy with macrocyclic polyoxazole
   Keisuke Iida^*, Yamato Tsushima, Yue Ma, Shadi Sedghi Masoud, Mai Sakuma, Tomomi Yokoyama, Wataru Yoshida, Kazunori Ikebukuro and Kazuo Nagasawa^*
   Bioorganic & Medicinal Chemistry (2019) 27 (8), 1742-1746; doi.org/10.1016/j.bmc.2019.02.056


6. Third generation impedimetric sensor employing direct electron transfer type glucose dehydrogenase
   Yuka Ito^†, Junko Okuda-Shimazaki^†, Wakako Tsugawa, Noya Loew, Isao Shitanda, Chi-En Lin, JeffreyLa Belle and Koji Sode^*
   Biosensors and Bioelectronics (2019) 129 (15), 189-197; doi.org/10.1016/j.bios.2019.01.018, †: Contributed equally


7. Anti-Idiotype DNA Aptamer Affinity Purification–High-Temperature Reversed-Phase Liquid Chromatography: A Simple, Accurate, and Selective Bioanalysis of Bevacizumab
   Tomohiro Yamada, Taro Saito, Yutaka Shimizu, Kaori Tsukakoshi, Hideki Hayashi, Hajime Mizuno, Daiki Tsuji, Keisuke Yamamoto, Kunihiko Itoh, Toshimasa Toyo’oka, Kazunori Ikebukuro and Kenichiro Todoroki^*
   Molecules (2019) 24 (5), 857; doi.org/10.3390/molecules24050857


8. High-Throughput Bioanalysis of Bevacizumab in Human Plasma Based on Enzyme-Linked Aptamer Assay Using Anti-Idiotype DNA Aptamer
   Tomohiro Yamada, Taro Saito, Yoshia Hill, Yutaka Shimizu, Kaori Tsukakoshi, Hajime Mizuno, Hideki Hayashi, Kazunori Ikebukuro, Toshimasa Toyo’oka, and Kenichiro Todoroki^*
   Analytical chemistry (2019) 91 (4), 3125-3130; doi.org/10.1021/acs.analchem.8b05725


9. Development of a third-generation glucose sensor based on the open circuit potential for continuous glucose monitoring
   Inyoung Lee, Noya Loew, Wakako Tsugawa, Kazunori Ikebukuro and Koji Sode^*
   Biosensors and Bioelectronics (2019) 124-125, 216-223; doi.org/10.1016/j.bios.2018.09.099


10. Designer fungus FAD glucose dehydrogenase capable of direct electron transfer
    Kohei Ito, Junko Okuda-Shimazaki, Kazushige Mori, Katsuhiro Kojima, Wakako Tsugawa, Kazunori Ikebukuro, Chi-En Lin, Jeffrey La Belle, Hiromi Yoshida and Koji Sode^*
    Biosensors and Bioelectronics (2019) 123, 114-123; doi.org/10.1016/j.bios.2018.07.027


11. Book:
    タンパク質のアモルファス凝集と溶解性-基礎研究からバイオ産業・創薬研究への応用まで-, 第III編 制御 第6章 巻き戻し法を用いた低分子抗体の調製
    浅野　竜太郎
    シーエムシー出版 (2019) , 211-218

2018年

1. Engineering the hinge region of human IgG1 Fc-fused bispecific antibodies to improve fragmentation resistance
   Saori Suzuki, Hiroaki Annaka, Shota Konno, Izumi Kumagai and Ryutaro Asano^*
   Scientific Reports (2018) 8, 17253; doi:10.1038/s41598-018-35489-y


2. Engineered fungus derived FAD-dependent glucose dehydrogenase with acquired ability to utilize hexaammineruthenium(III) as an electron acceptor
   Madoka Okurita, Nanami Suzuki, Noya Loew, Hiromi Yoshida, Wakako Tsugawa, Kazushige Mori, Katsuhiro Kojima, David C. Klonoff and Koji Sode^*
   Bioelectrochemistry (2018) 123, 62-69; doi.org/10.1016/j.bioelechem.2018.04.007


3. Selection and Characterization of DNA Aptamers Against FokI Nuclease Domain
   Maui Nishio, Ayana Yamagishi, Kaori Tsukakoshi, Yoshio Kato, Chikashi Nakamura and Kazunori Ikebukuro
   Zinc Finger Proteins (2018) 1867, 165-174; doi.org/10.1007/978-1-4939-8799-3_12


4. Chemo-enzymatic total syntheses of jorunnamycin A, saframycin A, and N-fmoc saframycin Y3
   Ryo Tanifuji, Kento Koketsu, Michiko Takakura, Ryutaro Asano, Atsushi Minami, Hideaki Oikawa^* and Hiroki Oguri^*
   Journal of the American Chemical Society (2018) 140 (34), 10705-10709; doi/abs/10.1021/jacs.8b07161


5. Esterification of PQQ Enhances Blood-Brain Barrier Permeability and Inhibitory Activity against Amyloidogenic Protein Fibril Formation
   Kaori Tsukakoshi, Wataru Yoshida, Masaki Kobayashi, Natsuki Kobayashi, Jihoon Kim, Toshisuke Kaku, Toshitsugu Iguchi, Kazuo Nagasawa, Ryutaro Asano, Kazunori Ikebukuro and Koji Sode^*
   ACS Chemical Neuroscience (2018) 9 (12), 2898-2903; doi.org/10.1021/acschemneuro.8b00355


6. Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production
   Kazuaki Hoshi, Tomohiko Yamazaki^*, Chiaki Yoshikawa, Wakako Tsugawa, Kazunori Ikebukuro and Koji Sode
   International Journal of Nanomedicine (2018) 13, 4461-4472; doi.org/10.2147/IJN.S166259


7. High-throughput cytotoxicity and antigen-binding assay for screening small bispecific antibodies without purification
   Aruto Sugiyama, Mitsuo Umetsu^*, Hikaru Nakazawa, Teppei Niide, Ryutaro Asano, Takamitsu Hattori and Izumi Kumagai
   Journal of Bioscience and Bioengineering (2018) 126 (2), 153-161; doi.org/10.1016/j.jbiosc.2018.02.007


8. Elucidation of the intra- and inter-molecular electron transfer pathways of glucoside 3-dehydrogenase
   Ryota Miyazaki^†, Tomohiko Yamazaki^†, Keiichi Yoshimatsu, Katsuhiro Kojima, Ryutaro Asano, Koji Sode^* and Wakako Tsugawa^*
   Bioelectrochemistry (2018) 122, 115-122; doi.org/10.1016/j.bioelechem.2018.03.001, †: Contributed equally


9. Review:
   Riboregulator elements as tools to engineer gene expression in cyanobacteria
   Kinuko Ueno, Kaori Tsukakoshi and Kazunori Ikebukuro^*
   Applied Microbiology and Biotechnology (2018) 102 (18), 7717-7723; doi.org/10.1007/s00253-018-9221-0


10. Comprehensive study of domain rearrangements of single-chain bispecific antibodies to determine the best combination of configurations and microbial host cells
    Ryutaro Asano^†, Yuri Kuroki^†, Sachiko Honma, Mihoko Akabane, Shunsuke Watanabe, Shinzo Mayuzumi, Shuichi Hiyamuta, Izumi Kumagai and Koji Sode
    mAbs (2018) 10 (6), 854-863; doi.org/10.1080/19420862.2018.1476815, †: Contributed equally


11. Construction and characterization of flavin adenine dinucleotide glucose dehydrogenase complex harboring a truncated electron transfer subunit
    Junko Okuda-Shimazaki^*, Noya Loew^*, Nana Hirose, Katsuhiro Kojima, Kazushige Mori, Wakako Tsugawa and Koji Sode^*
    Electrochimica Acta (2018) 277, 276-286; doi.org/10.1016/j.electacta.2018.04.060


12. Compact seahorse-shaped T cell-activating antibody for cancer therapy
    Hiroto Fujii, Yoshikazu Tanaka, Hikaru Nakazawa, Aruto Sugiyama, Noriyoshi Manabe, Akira Shinoda Nobutaka Shimizu, Takamitsu Hattori, Katsuhiro Hosokawa, Takuma Sujino, Tomoyuki Ito, Teppei Niide, Ryutaro Asano, Izumi Kumagai and Mitsuo Umetsu^*
    Advanced Therapeutics (2018) 1 (3), 1700031; doi.org/10.1002/adtp.201700031


13. Development of a glucose sensor employing quick and easy modification method with mediator for altering electron acceptor preference
    Mika Hatada, Noya Loew, Yuka Inose-Takahashi, Junko Okuda-Shimazaki, Wakako Tsugawa, Ashok Mulchandani and Koji Sode^*
    Bioelectrochemistry (2018) 121, 185-190; doi.org/10.1016/j.bioelechem.2018.02.001


14. The electrochemical behavior of a FAD dependent glucose dehydrogenase with direct electron transfer subunit by immobilization on self-assembled monolayers
    Inyoung Lee, Noya Loew, Wakako Tsugawa, Chi-En Lin, David Probst, Jeffrey T. La Belle and Koji Sode^*
    Bioelectrochemistry (2018) 121, 1-6; doi.org/10.1016/j.bioelechem.2017.12.008


15. Minimizing the effects of oxygen interference on l-lactate sensors by a single amino acid mutation in Aerococcus viridansl-lactate oxidase
    Kentaro Hiraka, Katsuhiro Kojima, Chi-En Lin, Wakako Tsugawa, Ryutaro Asano, Jeffrey T. La Belle^* and Koji Sode^*
    Biosensors and Bioelectronics (2018) 103, 163-170; doi.org/10.1016/j.bios.2017.12.018


16. CpG Methylation Changes G-Quadruplex Structures Derived from Gene Promoters and Interaction with VEGF and SP1
    Kaori Tsukakoshi^†, Shiori Saito^†, Wataru Yoshida^†, Shinichi Goto and Kazunori Ikebukuro^*
    Molecules (2018) 23 (4), 944; doi.org/10.3390/molecules23040944, †: Contributed equally


17. Mutagenesis study of the cytochrome c subunit responsible for the direct electron transfer-type catalytic activity of FAD-dependent glucose dehydrogenase
    Yuki Yamashita^†, Nanoha Suzuki^†, Nana Hirose, Katsuhiro Kojima, Wakako Tsugawa^* and Koji Sode^*
    International Journal of Molecular Sciences (2018) 19 (4), 931; doi.org/10.3390/ijms19040931, †: Contributed equally


18. Identification of G-quadruplex clusters by high-throughput sequencing of whole-genome amplified products with a G-quadruplex ligand
    Wataru Yoshida^*, Hiroki Saikyo, Kazuhiko Nakabayashi, Hitomi Yoshioka, Daniyah Habiballah Bay, Keisuke Iida, Tomoko Kawai, Kenichiro Hata, Kazunori Ikebukuro, Kazuo Nagasawa and Isao Karube
    Scientific Reports (2018) 8, 3116; doi.org/10.1038/s41598-018-21514-7


19. Structural considerations for functional anti-EGFR × anti-CD3 bispecific diabodies in light of domain order and binding affinity
    Ryutaro Asano^*, Keisuke Nagai, Koki Makabe, Kento Takahashi, Takashi Kumagai, Hiroko Kawaguchi, Hiromi Ogata, Kyoko Arai, Mitsuo Umetsu and Izumi Kumagai^*
    Oncotarget (2018) 9 (7), 13884-13893; doi.org/10.18632/oncotarget.24490


20. Improving the induction fold of riboregulators for cyanobacteria
    Ippei Sakamoto^†, Koichi Abe^†, Sumiya Kawai^†, Kaori Tsukakoshi^†, Yuta Sakai, Koji Sode and Kazunori Ikebukuro^*
    RNA Biology (2018) 15 (2), 353-358; doi.org/10.1080/15476286.2017.1422470, †: Contributed equally


21. Convenient and Universal Fabrication Method for Antibody?Enzyme Complexes as Sensing Elements Using the SpyCatcher/SpyTag System
    Hayato Kimura, Ryutaro Asano^*, Natsumi Tsukamoto, Wakako Tsugawa and Koji Sode
    Analytical Chemistry (2018) 90 (24), 14500-14506; doi.org/10.1021/acs.analchem.8b04344


22. Affinity sensor for haemoglobin A1c based on single-walled carbon nanotube field-effect transistor and fructosyl amino acid binding protein
    Mika Hatada, Thien-Toan Tran, Wakako Tsugawa, Koji Sode^* and Ashok Mulchandani^*
    Biosensors and Bioelectronics (2018) 129, 254-259; doi.org/10.1016/j.bios.2018.09.069


23. Affinity maturation of humanized anti-epidermal growth factor receptor antibody using a modified phage-based open sandwich selection method
    Hideaki Sanada, Kazuki Kobayashi, Kenji Oyama, Takamitsu Maru, Takeshi Nakanishi, Mitsuo Umetsu, Ryutaro Asano^* and Izumi Kumagai^*
    Scientific Reports (2018) 8, 5414; doi.org/10.1038/s41598-018-23796-3


24. Development toward a novel integrated tear lactate sensor using Schirmer test strip and engineered lactate oxidase
    CHi-En Lin^†, Kentaro Hiraka^†, Daniel Matloff, Jared Johns, Anna Deng, Koji Sode and Jeffrey La Belle^*
    Sensors and Actuators B: Chemical (2018) 270, 525-529; doi.org/10.1016/j.snb.2018.05.061, †: Contributed equally


25. Book:
    ドラッグデリバリーシステム-バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発, 第13章 低分子がん治療抗体の開発とその高機能化および動態解析
    浅野　竜太郎
    シーエムシー出版 (2018) , 108-114

2017年

1. Characterization of Electron Mediator Preference of Aerococcus viridans-Derived Lactate Oxidase for Use in Disposable Enzyme Sensor Strips
   Noya Loew^†, Maya Fitriana^†, Kentaro Hiraka, Koji Sode and Wakako Tsugawa^*
   Sensors and Materials (2017) 29 (12), 1703-1711; doi.org/10.18494/SAM.2017.1731, †: Contributed equally


2. Mediator preference of two different FAD-dependent glucose dehydrogenases employed in disposable enzyme glucose sensors
   Noya Loew, Wakako Tsugawa, Daichi Nagae, Katsuhiro Kojima and Koji Sode^*
   Sensors (2017) 17 (11), 2636; doi.org/10.3390/s17112636


3. Applying a riboregulator as a new chromosomal gene regulation tool for higher glycogen production in Synechocystis sp. PCC 6803
   Kinuko Ueno, Yuta Sakai, Chika Shono, Ippei Sakamoto, Kaori Tsukakoshi, Yukako Hihara, Koji Sode and Kazunori Ikebukuro^*
   Applied Microbiology and Biotechnology (2017) 101 (23-24), 8465-8474; doi.org/10.1007/s00253-017-8570-4


4. Development of HGF-Binding aptamers with the combination of G4 promoter-derived aptamer selection and in silico maturation
   Tomomi Yokoyama^†, Kaori Tsukakosh^†, Wataru Yoshida, Taiki Saito, Kentaro Teramoto, Nasa Savory, Koichi Abe and Kazunori Ikebukuro^*
   Biotechnology and Bioengineering (2017) 114 (10), 2196-2203; doi.org/10.1002/bit.26354, †: Contributed equally


5. Review:
   
6. Development of aptamers against unpurified proteins
   Shinichi Goto, Kaori Tsukakoshi and Kazunori Ikebukuro^*
   Biotechnology and Bioengineering (2017) 114 (12), 2706-2716; doi.org/10.1002/bit.26389


7. Continuous operation of an ultra-low-power microcontroller using glucose as the sole energy source
   Inyoung Lee, Takashi Sode, Noya Loew, Wakako Tsugawa, Christopher Robin Lowe and Koji Sode^*
   Biosensors and Bioelectronics (2017) 93, 335-339; doi.org/10.1016/j.bios.2016.09.095


8. Development of an electrochemical detection system for measuring DNA methylation levels using methyl CpG-Binding protein and glucose dehydrogenase-fused zinc finger protein
   Jinhee Lee, Wataru Yoshida, Koichi Abe, Kazuhiko Nakabayashi, Hironobu Wakeda, Kenichiro Hata, Christophe A. Marquette, Loic J. Blum, Koji Sode and Kazunori Ikebukuro^*
   Biosensors and Bioelectronics (2017) 93, 118-123; doi.org/10.1016/j.bios.2016.09.060


9. DNA Aptamers against FokI nuclease domain for genome editing applications
   Maui Nishio, Daisuke Matsumoto, Yoshio Kato, Koichi Abe, Jinhee Lee, Kaori Tsukakoshi, Ayana Yamagishi, Chikashi Nakamura and Kazunori Ikebukuro^*
   Biosensors and Bioelectronics (2017) 93, 26-31; doi.org/10.1016/j.bios.2016.11.042


10. Identification of G-Quadruplex structures that possess transcriptional regulating functions in the dele and Cdc6 CpG islands
    Daniyah H. Bay^†, Annika Busch^†, Fred Lisdat, Keisuke Iida, Kazunori Ikebukuro, Kazuo Nagasawa, Isao Karube and Wataru Yoshida^*
    BMC Molecular Biology (2017) 18, 17; doi.org/10.1186/s12867-017-0094-z, †: Contributed equally


11. A semi high-throughput method for screening small bispecific antibodies with high cytotoxicity
    Aruto Sugiyama, Mitsuo Umetsu^*, Hikaru Nakazawa, Teppei Niide, Tomoko Onodera, Katsuhiro Hosokawa, Shuhei Hattori, Ryutaro Asano and Izumi Kumagai^*
    Scientific Reports (2017) 7, 2862; doi.org/10.1038/s41598-017-03101-4


12. Development of a screen-printed carbon electrode based disposable enzyme sensor strip for the measurement of glycated albumin
    Mika Hatada, Wakako Tsugawa, Eri Kamio, Noya Loew, David C. Klonoff and Koji Sode^*
    Biosensors and Bioelectronics (2017) 88, 167-173; doi.org/10.1038/s41598-017-03101-4


13. Novel fungal FAD glucose dehydrogenase derived from Aspergillus niger for glucose enzyme sensor strips
    Koji Sode^*, Noya Loew, Yosuke Ohnishi, Hayato Tsuruta, Kazushige Mori, Katsuhiro Kojima, Wakako Tsugawa, Jeffrey T. LaBelle and David C. Klonoff
    Biosensors and Bioelectronics (2017) 87, 305-311; doi.org/10.1016/j.bios.2016.08.053


14. Generation of camelid VHH bispecific constructs via in-cell intein-mediated protein trans-splicing
    Yuki Shibuya, Natsuki Haga, Ryutaro Asano, Hikaru Nakazawa, Takamitsu Hattori, Daisuke Takeda, Aruto Sugiyama, Reiko Kurotani, Izumi Kumagai, Mitsuo Umetsu and Koki Makabe^*
    Protein Engineering, Design and Selection (2017) 30 (1), 15-21; doi.org/10.1093/protein/gzw057


15. Mediator preference of two different FAD-dependent glucose dehydrogenases employed in disposable enzyme glucose sensors
    Noya Loew, Wakako Tsugawa, Daichi Nagae, Katsuhiro Kojima and Koji Sode^*
    Sensors (2017) 17 (11), 2636; doi.org/10.3390/s17112636


16. Review:
    人工改変を駆使した高機能性次世代がん治療抗体の開発
    浅野　竜太郎, 熊谷　泉
    月刊ファインケミカル (2017) 46 (2), 13-18

2016年

1. ATP-mediated release of a DNA-binding protein from a silicon nanoneedle array
   Daisuke Matsumoto, Maui Nishio, Yoshio Kato, Wataru Yoshida, Koichi Abe, Kyoko Fukazawa, Kazuhiro Ishihara, Futoshi Iwata, Kazunori Ikebukuro and Chikashi Nakamura^*
   Electrochemistry (2016) 84 (5), 305-307; doi.org/10.5796/electrochemistry.84.305


2. Detection of DNA methylation of G-quadruplex and i-motif-forming sequences by measuring the initial elongation efficiency of polymerase chain reation
   Wataru Yoshida^*, Hitomi Yoshioka, Daniyah Habiballah Bay, Keisuke Iida, Kazunori Ikebukuro, Kazuo Nagasawa and Isao Karube
   Analytical Chemistry (2016) 88 (14), 7101-7107; doi.org/10.1021/acs.analchem.6b00982


3. Review:
   Methods for improving aptamer binding affinity
   Hijiri Hasegawa, Nasa Savory, Koichi Abe and Kazunori Ikebukuro^*
   Molecules (2016) 21 (4), 421; doi.org/10.3390/molecules21040421


4. Structural regulation by a G-quadruplex ligand increases binding abilities of G-quadruplex-forming aptamers
   Kaori Tsukakoshi, Yuri Ikuta, Koichi Abe, Wataru Yoshida, Keisuke Iida, Yue Ma, Kazuo Nagasawa, Koji Sode and Kazunori Ikebukuro^*
   Chemical Communications (2016) 52 (85), 12646-12649; doi.org/10.1039/C6CC07552E


5. An Fe-S cluster in the conserved Cys-rich region in the catalytic subunit of FAD-dependent dehydrogenase complexes
   Masaki Shiota, Tomohiko Yamazaki, Keiichi Yoshimatsu, Katsuhiro Kojima, Wakako Tsugawa, Stefano Ferri and Koji Sode^*
   Bioelectrochemistry (2016) 112, 178-183; doi.org/10.1016/j.bioelechem.2016.01.010


6. Review:
   
7. BioCapacitor: A novel principle for biosensors
   Koji Sode^*, Tomohiko Yamazaki, Inyoung Lee, Takuya Hanashi and Wakako Tsugawa
   Biosensors and Bioelectronics (2016) 76, 20-28; doi.org/10.1016/j.bios.2015.07.065


8. Electrochemical sensing system employing fructosamine 6-kinase enables glycated albumin measurement requing no proteolytic digestion
   Miho Kameya, Wakako Tsugawa, Mayumi Yamada-Tajima, Mika Hatada, Keita Suzuki, Akane Sakaguchi-Mikami, Stefano Ferri, David C. Klonoff and Koji Sode^*
   Biotechnology Journal (2016) 11 (6), 797-804; doi.org/10.1002/biot.201500442


9. Anti-EGFR scFv tetramer (tetrabody) with a stable monodisperse structure, strong anticancer effect, and a long in vivo half-life
   Ryutaro Asano^*, Noriaki Koyama, Yasuyo Hagiwara, Yosuke Masakari, Ryota Orimo, Kyoko Arai, Hiromi Ogata, Shozo Furumoto, Mitsuo Umetsu and Izumi Kumagai^*
   FEBS Open Bio (2016) 6 (6), 594-602; doi.org/10.1002/2211-5463.12073


10. Review:
    人工抗体の機能的構造形態に関する研究
    浅野　竜太郎
    生化学 (2016) 88 (4), 380-385


11. Review:
    がん治療を目指した二重特異性抗体の開発
    浅野　竜太郎, 熊谷　泉
    細胞 (2016) 48 (4), 8-12


12. Review:
    次世代がん治療薬を目指した低分子二重特異性抗体の開発と高機能化
    浅野　竜太郎, 熊谷　泉
    酵素工学ニュース (2016) 75, 11-14

||最新-2021年|| ||2020-2016年|| ||2015年-2011年|| ||2010年-2006年|| ||2005年-2001年|| ||2000年-1996年|| ||1995年-1986年||