池袋・津川・浅野 研究室 論文
||最新-2021年|| ||2020-2016年|| ||2015年-2011年|| ||2010年-2006年|| ||2005年-2001年|| ||2000年-1996年|| ||1995年-1986年||

2020年

  1. Functional Domain Order of an Anti-EGFR × Anti-CD16 Bispecific Diabody Involving NK Cell Activation
    Atsushi Kuwahara, Keisuke Nagai, Takeshi Nakanishi, Izumi Kumagai and Ryutaro Asano*
    International Journal of Molecular Sciences (2020) 21 (23), 8914; doi.org/10.3390/ijms21238914

  2. Creation of a novel DET type FAD glucose dehydrogenase harboring Escherichia coli derived cytochrome b562 as an electron transfer domain
    Takumi Yanase, Junko Okuda-Shimazaki, Kazushige Mori, Katsuhiro Kojima, Wakako Tsugawa and Koji Sode*
    Biochemical and Biophysical Research Communications (2020) 530 (1), 82-86; doi.org/10.1016/j.bbrc.2020.06.132,
    †: Contributed equally

  3. A Green Light-Regulated T7 RNA Polymerase Gene Expression System for Cyanobacteria
    Chika Shono, Dwi Ariyanti, Koichi Abe, Yuta Sakai, Ippei Sakamoto, Kaori Tsukakoshi, Koji Sode* and Kazunori Ikebukuro*
    Marine Biotechnology (2020); doi.org/10.1007/s10126-020-09997-w, †: Contributed equally

  4. Monomeric G-Quadruplex-Based CpG Oligodeoxynucleotides as Potent Toll-Like Receptor 9 Agonists
    Anh Thi Tram Tu, Kazuaki Hoshi, Kazunori Ikebukuro, Nobutaka Hanagata and Tomohiko Yamazaki*
    Biomacromolecules (2020) 21 (9), 3644-3657; doi.org/10.1021/acs.biomac.0c00679

  5. Association behavior and control of the quality of cancer therapeutic Tbispecific diabodies expressed in Escherichia coli
    Hikaru Nakazawa, Tomoko Onodera-Sugano, Aruto Sugiyama, Yoshikazu Tanaka, Takamitsu Hattori, Teppei Niide, Hiromi Ogata, Ryutaro Asano, Izumi Kumagai and Mitsuo Umetsu*
    Biochemical Engineering Journal (2020) 160, 107636; doi.org/10.1016/j.bej.2020.107636

  6. Application of a Glucose Dehydrogenase-Fused with Zinc Finger Protein to Label DNA Aptamers for the Electrochemical Detection of VEGF
    Jinhee Lee, Atsuro Tatsumi, Kaori Tsukakoshi, Ellie D. Wilson, Koichi Abe, Koji Sode and Kazunori Ikebukuro*
    Sensors (2020) 20 (14), 3878; doi.org/10.3390/s20143878, †: Contributed equally

  7. Review:
    Alteration of Electron Acceptor Preferences in the Oxidative Half-Reaction of Flavin-Dependent Oxidases and Dehydrogenases
    Kentaro Hiraka, Wakako Tsugawa and Koji Sode*
    International Journal of Molecular Sciences (2020) 21 (11), 3797; doi.org/10.3390/ijms21113797

  8. Build-up functionalization of anti-EGFR × anti-CD3 bispecific diabodies by integrating high-affinity mutants and functional molecular formats
    Ryutaro Asano*, Katsuhiro Hosokawa, Shintaro Taki, Shota Konno, Ippei Shimomura, Hiromi Ogata, Mai Okada, Kyoko Arai, Masayoshi Onitsuka, Takeshi Omasa, Takeshi Nakanishi, Mitsuo Umetsu and Izumi Kumagai*
    Scientific Reports (2020) 10, 4913; doi.org/10.1038/s41598-020-61840-3

  9. Employment of 1-Methoxy-5-Ethyl Phenazinium Ethyl Sulfate as a Stable Electron Mediator in Flavin Oxidoreductases-Based Sensors
    Maya Fitriana, Noya Loew, Arief Budi Witarto, Kazunori Ikebukuro, Koji Sode* and Wakako Tsugawa*
    Sensors (2020) 20 (10), 2825; doi.org/10.3390/s20102825

  10. Rational engineering of Aerococcus viridans l-lactate oxidase for the mediator modification to achieve quasi-direct electron transfer type lactate sensor
    Kentaro Hiraka, Katsuhiro Kojima, Wakako Tsugawa, Ryutaro Asano, Kazunori Ikebukuro and Koji Sode*
    Biosensors and Bioelectronics (2020) 151, 111974; doi.org/10.1016/j.bios.2019.111974

  11. Construction of a circularly connected VHH bispecific antibody (cyclobody) for the desirable positioning of antigen-binding sites
    Saki Hemmi, Ryutaro Asano, Kouki Kimura, Mitsuo Umetsu, Takeshi Nakanishi, Izumi Kumagai and Koki Makabe*
    Biochemical and Biophysical Research Communications (2020) 523, 72-77; doi.org/10.1016/j.bbrc.2019.12.018

  12. Engineered Glucose Oxidase Capable of Quasi-Direct Electron Transfer after a Quick-and-Easy Modification with a Mediator
    Nanami Suzuki, Jinhee Lee, Noya Loew, Yuka Takahashi-Inose, Junko Okuda-Shimazaki, Katsuhiro Kojima, Kazushige Mori, Wakako Tsugawa and Koji Sode*
    International Journal of Molecular Sciences (2020) 21 (3), 1137; doi.org/10.3390/ijms21031137, †: Contributed equally

  13. Ethanol Detection at the Parts per Billion Level with Single‐Stranded‐DNA‐Modified Graphene Field‐Effect Transistors
    Ryo Nozaki, Takashi Ikuta, Kinuko Ueno, Kaori Tsukakoshi, Kazunori Ikebukuro and Kenzo Maehashi
    Physica Status Solidi B-Basic Solid State Physics (2020) 257 (2); doi.org/10.1002/pssb.201900376

  14. Chemically Crosslinked Bispecific Antibodies for Cancer Therapy: Breaking from the Structural Restrictions of the Genetic Fusion Approach
    Asami Ueda, Mitsuo Umetsu*, Takeshi Nakanishi, Kentaro Hashikami, Hikaru Nakazawa, Shuhei Hattori, Ryutaro Asano and Izumi Kumagai*
    International Journal of Molecular Sciences (2020) 21 (3), 711; doi.org/10.3390/ijms21030711

  15. 2019年

    1. Application of an engineered chromatic acclimation sensor for red-light-regulated gene expression in cyanobacteria
      Shunichi Kobayashi, Mitsuharu Nakajima, Ryutaro Asano, Eunice A. Ferreira, Koichi Abe, Paula Tamagnini, Shota Atsumi and Koji Sode*
      Algal Research (2019) 44, 101691; doi.org/10.1016/j.algal.2019.101691

    2. X-ray structure of the direct electron transfer-type FAD glucose dehydrogenase catalytic subunit complexed with a hitchhiker protein
      Hiromi Yoshida, Katsuhiro Kojima, Masaki Shiota, Keiichi Yoshimatsu, Tomohiko Yamazaki, Sterano Ferri, Wakako Tsugawa, Shigehiro Kamitori and Koji Sode*
      Acta Crystallographica Section D (2019) 75 (9), 841-851; doi.org/10.1107/S2059798319010878

    3. G-Quadruplex Structure Improves the Immunostimulatory Effects of Cytosine-Phosphate-Guanine Oligonucleotides
      Kazuaki Hoshi, Tomohiko Yamazaki*, Yuuki Sugiyama, Kaori Tsukakoshi, Wakako Tsugawa, Koji Sode and Kazunori Ikebukuro
      Nucleic Acid Therapeutics (2019) 29 (4), 224-229; doi.org/10.1089/nat.2018.0761

    4. Generation of C5-desoxy analogs of tetrahydroisoquinoline alkaloids exhibiting potent DNA alkylating ability
      Ryo Tanifuji, Kaori Tsukakoshi, Kazunori Ikebukuro, Hideaki Oikawa and Hiroki Oguri*
      Bioorganic & Medicinal Chemistry Letters (2019) 29 (14), 1807-1811; doi.org/10.1016/j.bmcl.2019.05.009

    5. Model studies for isolation of G-quadruplex-forming DNA sequences through a pull-down strategy with macrocyclic polyoxazole
      Keisuke Iida*, Yamato Tsushima, Yue Ma, Shadi Sedghi Masoud, Mai Sakuma, Tomomi Yokoyama, Wataru Yoshida, Kazunori Ikebukuro and Kazuo Nagasawa*
      Bioorganic & Medicinal Chemistry (2019) 27 (8), 1742-1746; doi.org/10.1016/j.bmc.2019.02.056

    6. Third generation impedimetric sensor employing direct electron transfer type glucose dehydrogenase
      Yuka Ito, Junko Okuda-Shimazaki, Wakako Tsugawa, Noya Loew, Isao Shitanda, Chi-En Lin, JeffreyLa Belle and Koji Sode*
      Biosensors and Bioelectronics (2019) 129 (15), 189-197; doi.org/10.1016/j.bios.2019.01.018, †: Contributed equally

    7. Anti-Idiotype DNA Aptamer Affinity Purification–High-Temperature Reversed-Phase Liquid Chromatography: A Simple, Accurate, and Selective Bioanalysis of Bevacizumab
      Tomohiro Yamada, Taro Saito, Yutaka Shimizu, Kaori Tsukakoshi, Hideki Hayashi, Hajime Mizuno, Daiki Tsuji, Keisuke Yamamoto, Kunihiko Itoh, Toshimasa Toyo’oka, Kazunori Ikebukuro and Kenichiro Todoroki*
      Molecules (2019) 24 (5), 857; doi.org/10.3390/molecules24050857

    8. High-Throughput Bioanalysis of Bevacizumab in Human Plasma Based on Enzyme-Linked Aptamer Assay Using Anti-Idiotype DNA Aptamer
      Tomohiro Yamada, Taro Saito, Yoshia Hill, Yutaka Shimizu, Kaori Tsukakoshi, Hajime Mizuno, Hideki Hayashi, Kazunori Ikebukuro, Toshimasa Toyo’oka, and Kenichiro Todoroki*
      Analytical chemistry (2019) 91 (4), 3125-3130; doi.org/10.1021/acs.analchem.8b05725

    9. Development of a third-generation glucose sensor based on the open circuit potential for continuous glucose monitoring
      Inyoung Lee, Noya Loew, Wakako Tsugawa, Kazunori Ikebukuro and Koji Sode*
      Biosensors and Bioelectronics (2019) 124-125, 216-223; doi.org/10.1016/j.bios.2018.09.099

    10. Designer fungus FAD glucose dehydrogenase capable of direct electron transfer
      Kohei Ito, Junko Okuda-Shimazaki, Kazushige Mori, Katsuhiro Kojima, Wakako Tsugawa, Kazunori Ikebukuro, Chi-En Lin, Jeffrey La Belle, Hiromi Yoshida and Koji Sode*
      Biosensors and Bioelectronics (2019) 123, 114-123; doi.org/10.1016/j.bios.2018.07.027

    11. Book:
      タンパク質のアモルファス凝集と溶解性-基礎研究からバイオ産業・創薬研究への応用まで-, 第III編 制御 第6章 巻き戻し法を用いた低分子抗体の調製
      浅野 竜太郎
      シーエムシー出版 (2019) , 211-218


2018年

  1. Engineering the hinge region of human IgG1 Fc-fused bispecific antibodies to improve fragmentation resistance
    Saori Suzuki, Hiroaki Annaka, Shota Konno, Izumi Kumagai and Ryutaro Asano*
    Scientific Reports (2018) 8, 17253; doi:10.1038/s41598-018-35489-y

  2. Engineered fungus derived FAD-dependent glucose dehydrogenase with acquired ability to utilize hexaammineruthenium(III) as an electron acceptor
    Madoka Okurita, Nanami Suzuki, Noya Loew, Hiromi Yoshida, Wakako Tsugawa, Kazushige Mori, Katsuhiro Kojima, David C. Klonoff and Koji Sode*
    Bioelectrochemistry (2018) 123, 62-69; doi.org/10.1016/j.bioelechem.2018.04.007

  3. Selection and Characterization of DNA Aptamers Against FokI Nuclease Domain
    Maui Nishio, Ayana Yamagishi, Kaori Tsukakoshi, Yoshio Kato, Chikashi Nakamura and Kazunori Ikebukuro
    Zinc Finger Proteins (2018) 1867, 165-174; doi.org/10.1007/978-1-4939-8799-3_12

  4. Chemo-enzymatic total syntheses of jorunnamycin A, saframycin A, and N-fmoc saframycin Y3
    Ryo Tanifuji, Kento Koketsu, Michiko Takakura, Ryutaro Asano, Atsushi Minami, Hideaki Oikawa* and Hiroki Oguri*
    Journal of the American Chemical Society (2018) 140 (34), 10705-10709; doi/abs/10.1021/jacs.8b07161

  5. Esterification of PQQ Enhances Blood-Brain Barrier Permeability and Inhibitory Activity against Amyloidogenic Protein Fibril Formation
    Kaori Tsukakoshi, Wataru Yoshida, Masaki Kobayashi, Natsuki Kobayashi, Jihoon Kim, Toshisuke Kaku, Toshitsugu Iguchi, Kazuo Nagasawa, Ryutaro Asano, Kazunori Ikebukuro and Koji Sode*
    ACS Chemical Neuroscience (2018) 9 (12), 2898-2903; doi.org/10.1021/acschemneuro.8b00355

  6. Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production
    Kazuaki Hoshi, Tomohiko Yamazaki*, Chiaki Yoshikawa, Wakako Tsugawa, Kazunori Ikebukuro and Koji Sode
    International Journal of Nanomedicine (2018) 13, 4461-4472; doi.org/10.2147/IJN.S166259

  7. High-throughput cytotoxicity and antigen-binding assay for screening small bispecific antibodies without purification
    Aruto Sugiyama, Mitsuo Umetsu*, Hikaru Nakazawa, Teppei Niide, Ryutaro Asano, Takamitsu Hattori and Izumi Kumagai
    Journal of Bioscience and Bioengineering (2018) 126 (2), 153-161; doi.org/10.1016/j.jbiosc.2018.02.007

  8. Elucidation of the intra- and inter-molecular electron transfer pathways of glucoside 3-dehydrogenase
    Ryota Miyazaki, Tomohiko Yamazaki, Keiichi Yoshimatsu, Katsuhiro Kojima, Ryutaro Asano, Koji Sode* and Wakako Tsugawa*
    Bioelectrochemistry (2018) 122, 115-122; doi.org/10.1016/j.bioelechem.2018.03.001, †: Contributed equally

  9. Review:
    Riboregulator elements as tools to engineer gene expression in cyanobacteria
    Kinuko Ueno, Kaori Tsukakoshi and Kazunori Ikebukuro*
    Applied Microbiology and Biotechnology (2018) 102 (18), 7717-7723; doi.org/10.1007/s00253-018-9221-0

  10. Comprehensive study of domain rearrangements of single-chain bispecific antibodies to determine the best combination of configurations and microbial host cells
    Ryutaro Asano, Yuri Kuroki, Sachiko Honma, Mihoko Akabane, Shunsuke Watanabe, Shinzo Mayuzumi, Shuichi Hiyamuta, Izumi Kumagai and Koji Sode
    mAbs (2018) 10 (6), 854-863; doi.org/10.1080/19420862.2018.1476815, †: Contributed equally

  11. Construction and characterization of flavin adenine dinucleotide glucose dehydrogenase complex harboring a truncated electron transfer subunit
    Junko Okuda-Shimazaki*, Noya Loew*, Nana Hirose, Katsuhiro Kojima, Kazushige Mori, Wakako Tsugawa and Koji Sode*
    Electrochimica Acta (2018) 277, 276-286; doi.org/10.1016/j.electacta.2018.04.060

  12. Compact seahorse-shaped T cell-activating antibody for cancer therapy
    Hiroto Fujii, Yoshikazu Tanaka, Hikaru Nakazawa, Aruto Sugiyama, Noriyoshi Manabe, Akira Shinoda Nobutaka Shimizu, Takamitsu Hattori, Katsuhiro Hosokawa, Takuma Sujino, Tomoyuki Ito, Teppei Niide, Ryutaro Asano, Izumi Kumagai and Mitsuo Umetsu*
    Advanced Therapeutics (2018) 1 (3), 1700031; doi.org/10.1002/adtp.201700031

  13. Development of a glucose sensor employing quick and easy modification method with mediator for altering electron acceptor preference
    Mika Hatada, Noya Loew, Yuka Inose-Takahashi, Junko Okuda-Shimazaki, Wakako Tsugawa, Ashok Mulchandani and Koji Sode*
    Bioelectrochemistry (2018) 121, 185-190; doi.org/10.1016/j.bioelechem.2018.02.001

  14. The electrochemical behavior of a FAD dependent glucose dehydrogenase with direct electron transfer subunit by immobilization on self-assembled monolayers
    Inyoung Lee, Noya Loew, Wakako Tsugawa, Chi-En Lin, David Probst, Jeffrey T. La Belle and Koji Sode*
    Bioelectrochemistry (2018) 121, 1-6; doi.org/10.1016/j.bioelechem.2017.12.008

  15. Minimizing the effects of oxygen interference on l-lactate sensors by a single amino acid mutation in Aerococcus viridansl-lactate oxidase
    Kentaro Hiraka, Katsuhiro Kojima, Chi-En Lin, Wakako Tsugawa, Ryutaro Asano, Jeffrey T. La Belle* and Koji Sode*
    Biosensors and Bioelectronics (2018) 103, 163-170; doi.org/10.1016/j.bios.2017.12.018

  16. CpG Methylation Changes G-Quadruplex Structures Derived from Gene Promoters and Interaction with VEGF and SP1
    Kaori Tsukakoshi, Shiori Saito, Wataru Yoshida, Shinichi Goto and Kazunori Ikebukuro*
    Molecules (2018) 23 (4), 944; doi.org/10.3390/molecules23040944, †: Contributed equally

  17. Mutagenesis study of the cytochrome c subunit responsible for the direct electron transfer-type catalytic activity of FAD-dependent glucose dehydrogenase
    Yuki Yamashita, Nanoha Suzuki, Nana Hirose, Katsuhiro Kojima, Wakako Tsugawa* and Koji Sode*
    International Journal of Molecular Sciences (2018) 19 (4), 931; doi.org/10.3390/ijms19040931, †: Contributed equally

  18. Identification of G-quadruplex clusters by high-throughput sequencing of whole-genome amplified products with a G-quadruplex ligand
    Wataru Yoshida*, Hiroki Saikyo, Kazuhiko Nakabayashi, Hitomi Yoshioka, Daniyah Habiballah Bay, Keisuke Iida, Tomoko Kawai, Kenichiro Hata, Kazunori Ikebukuro, Kazuo Nagasawa and Isao Karube
    Scientific Reports (2018) 8, 3116; doi.org/10.1038/s41598-018-21514-7

  19. Structural considerations for functional anti-EGFR × anti-CD3 bispecific diabodies in light of domain order and binding affinity
    Ryutaro Asano*, Keisuke Nagai, Koki Makabe, Kento Takahashi, Takashi Kumagai, Hiroko Kawaguchi, Hiromi Ogata, Kyoko Arai, Mitsuo Umetsu and Izumi Kumagai*
    Oncotarget (2018) 9 (7), 13884-13893; doi.org/10.18632/oncotarget.24490

  20. Improving the induction fold of riboregulators for cyanobacteria
    Ippei Sakamoto, Koichi Abe, Sumiya Kawai, Kaori Tsukakoshi, Yuta Sakai, Koji Sode and Kazunori Ikebukuro*
    RNA Biology (2018) 15 (2), 353-358; doi.org/10.1080/15476286.2017.1422470, †: Contributed equally

  21. Convenient and Universal Fabrication Method for Antibody?Enzyme Complexes as Sensing Elements Using the SpyCatcher/SpyTag System
    Hayato Kimura, Ryutaro Asano*, Natsumi Tsukamoto, Wakako Tsugawa and Koji Sode
    Analytical Chemistry (2018) 90 (24), 14500-14506; doi.org/10.1021/acs.analchem.8b04344

  22. Selection and Characterization of DNA Aptamers Against FokI Nuclease Domain
    Maui Nishio, Ayana Yamagishi, Kaori Tsukakoshi, Yoshio Kato, Chikashi Nakamura and Kazunori Ikebukuro
    Zinc Finger Proteins (2018) 1867, 165-174; doi.org/10.1007/978-1-4939-8799-3_12

  23. Affinity sensor for haemoglobin A1c based on single-walled carbon nanotube field-effect transistor and fructosyl amino acid binding protein
    Mika Hatada, Thien-Toan Tran, Wakako Tsugawa, Koji Sode* and Ashok Mulchandani*
    Biosensors and Bioelectronics (2018) 129, 254-259; doi.org/10.1016/j.bios.2018.09.069

  24. Affinity maturation of humanized anti-epidermal growth factor receptor antibody using a modified phage-based open sandwich selection method
    Hideaki Sanada, Kazuki Kobayashi, Kenji Oyama, Takamitsu Maru, Takeshi Nakanishi, Mitsuo Umetsu, Ryutaro Asano* and Izumi Kumagai*
    Scientific Reports (2018) 8, 5414; doi.org/10.1038/s41598-018-23796-3

  25. Development toward a novel integrated tear lactate sensor using Schirmer test strip and engineered lactate oxidase
    CHi-En Lin, Kentaro Hiraka, Daniel Matloff, Jared Johns, Anna Deng, Koji Sode and Jeffrey La Belle*
    Sensors and Actuators B: Chemical (2018) 270, 525-529; doi.org/10.1016/j.snb.2018.05.061, †: Contributed equally

  26. Book:
    ドラッグデリバリーシステム-バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発, 第13章 低分子がん治療抗体の開発とその高機能化および動態解析
    浅野 竜太郎
    シーエムシー出版 (2018) , 108-114


2017年

  1. Characterization of Electron Mediator Preference of Aerococcus viridans-Derived Lactate Oxidase for Use in Disposable Enzyme Sensor Strips
    Noya Loew, Maya Fitriana, Kentaro Hiraka, Koji Sode and Wakako Tsugawa*
    Sensors and Materials (2017) 29 (12), 1703-1711; doi.org/10.18494/SAM.2017.1731, †: Contributed equally

  2. Mediator preference of two different FAD-dependent glucose dehydrogenases employed in disposable enzyme glucose sensors
    Noya Loew, Wakako Tsugawa, Daichi Nagae, Katsuhiro Kojima and Koji Sode*
    Sensors (2017) 17 (11), 2636; doi.org/10.3390/s17112636

  3. Applying a riboregulator as a new chromosomal gene regulation tool for higher glycogen production in Synechocystis sp. PCC 6803
    Kinuko Ueno, Yuta Sakai, Chika Shono, Ippei Sakamoto, Kaori Tsukakoshi, Yukako Hihara, Koji Sode and Kazunori Ikebukuro*
    Applied Microbiology and Biotechnology (2017) 101 (23-24), 8465-8474; doi.org/10.1007/s00253-017-8570-4

  4. Development of HGF-Binding aptamers with the combination of G4 promoter-derived aptamer selection and in silico maturation
    Tomomi Yokoyama, Kaori Tsukakosh, Wataru Yoshida, Taiki Saito, Kentaro Teramoto, Nasa Savory, Koichi Abe and Kazunori Ikebukuro*
    Biotechnology and Bioengineering (2017) 114 (10), 2196-2203; doi.org/10.1002/bit.26354, †: Contributed equally

  5. Review:
  6. Development of aptamers against unpurified proteins
    Shinichi Goto, Kaori Tsukakoshi and Kazunori Ikebukuro*
    Biotechnology and Bioengineering (2017) 114 (12), 2706-2716; doi.org/10.1002/bit.26389

  7. Continuous operation of an ultra-low-power microcontroller using glucose as the sole energy source
    Inyoung Lee, Takashi Sode, Noya Loew, Wakako Tsugawa, Christopher Robin Lowe and Koji Sode*
    Biosensors and Bioelectronics (2017) 93, 335-339; doi.org/10.1016/j.bios.2016.09.095

  8. Development of an electrochemical detection system for measuring DNA methylation levels using methyl CpG-Binding protein and glucose dehydrogenase-fused zinc finger protein
    Jinhee Lee, Wataru Yoshida, Koichi Abe, Kazuhiko Nakabayashi, Hironobu Wakeda, Kenichiro Hata, Christophe A. Marquette, Loic J. Blum, Koji Sode and Kazunori Ikebukuro*
    Biosensors and Bioelectronics (2017) 93, 118-123; doi.org/10.1016/j.bios.2016.09.060

  9. DNA Aptamers against FokI nuclease domain for genome editing applications
    Maui Nishio, Daisuke Matsumoto, Yoshio Kato, Koichi Abe, Jinhee Lee, Kaori Tsukakoshi, Ayana Yamagishi, Chikashi Nakamura and Kazunori Ikebukuro*
    Biosensors and Bioelectronics (2017) 93, 26-31; doi.org/10.1016/j.bios.2016.11.042

  10. Identification of G-Quadruplex structures that possess transcriptional regulating functions in the dele and Cdc6 CpG islands
    Daniyah H. Bay, Annika Busch, Fred Lisdat, Keisuke Iida, Kazunori Ikebukuro, Kazuo Nagasawa, Isao Karube and Wataru Yoshida*
    BMC Molecular Biology (2017) 18, 17; doi.org/10.1186/s12867-017-0094-z, †: Contributed equally

  11. A semi high-throughput method for screening small bispecific antibodies with high cytotoxicity
    Aruto Sugiyama, Mitsuo Umetsu*, Hikaru Nakazawa, Teppei Niide, Tomoko Onodera, Katsuhiro Hosokawa, Shuhei Hattori, Ryutaro Asano and Izumi Kumagai*
    Scientific Reports (2017) 7, 2862; doi.org/10.1038/s41598-017-03101-4

  12. Development of a screen-printed carbon electrode based disposable enzyme sensor strip for the measurement of glycated albumin
    Mika Hatada, Wakako Tsugawa, Eri Kamio, Noya Loew, David C. Klonoff and Koji Sode*
    Biosensors and Bioelectronics (2017) 88, 167-173; doi.org/10.1038/s41598-017-03101-4

  13. Novel fungal FAD glucose dehydrogenase derived from Aspergillus niger for glucose enzyme sensor strips
    Koji Sode*, Noya Loew, Yosuke Ohnishi, Hayato Tsuruta, Kazushige Mori, Katsuhiro Kojima, Wakako Tsugawa, Jeffrey T. LaBelle and David C. Klonoff
    Biosensors and Bioelectronics (2017) 87, 305-311; doi.org/10.1016/j.bios.2016.08.053

  14. Generation of camelid VHH bispecific constructs via in-cell intein-mediated protein trans-splicing
    Yuki Shibuya, Natsuki Haga, Ryutaro Asano, Hikaru Nakazawa, Takamitsu Hattori, Daisuke Takeda, Aruto Sugiyama, Reiko Kurotani, Izumi Kumagai, Mitsuo Umetsu and Koki Makabe*
    Protein Engineering, Design and Selection (2017) 30 (1), 15-21; doi.org/10.1093/protein/gzw057

  15. Mediator preference of two different FAD-dependent glucose dehydrogenases employed in disposable enzyme glucose sensors
    Noya Loew, Wakako Tsugawa, Daichi Nagae, Katsuhiro Kojima and Koji Sode*
    Sensors (2017) 17 (11), 2636; doi.org/10.3390/s17112636

  16. Review:
    人工改変を駆使した高機能性次世代がん治療抗体の開発
    浅野 竜太郎, 熊谷 泉
    月刊ファインケミカル (2017) 46 (2), 13-18

2016年

  1. ATP-mediated release of a DNA-binding protein from a silicon nanoneedle array
    Daisuke Matsumoto, Maui Nishio, Yoshio Kato, Wataru Yoshida, Koichi Abe, Kyoko Fukazawa, Kazuhiro Ishihara, Futoshi Iwata, Kazunori Ikebukuro and Chikashi Nakamura*
    Electrochemistry (2016) 84 (5), 305-307; doi.org/10.5796/electrochemistry.84.305

  2. Detection of DNA methylation of G-quadruplex and i-motif-forming sequences by measuring the initial elongation efficiency of polymerase chain reation
    Wataru Yoshida*, Hitomi Yoshioka, Daniyah Habiballah Bay, Keisuke Iida, Kazunori Ikebukuro, Kazuo Nagasawa and Isao Karube
    Analytical Chemistry (2016) 88 (14), 7101-7107; doi.org/10.1021/acs.analchem.6b00982

  3. Review:
    Methods for improving aptamer binding affinity
    Hijiri Hasegawa, Nasa Savory, Koichi Abe and Kazunori Ikebukuro*
    Molecules (2016) 21 (4), 421; doi.org/10.3390/molecules21040421

  4. Structural regulation by a G-quadruplex ligand increases binding abilities of G-quadruplex-forming aptamers
    Kaori Tsukakoshi, Yuri Ikuta, Koichi Abe, Wataru Yoshida, Keisuke Iida, Yue Ma, Kazuo Nagasawa, Koji Sode and Kazunori Ikebukuro*
    Chemical Communications (2016) 52 (85), 12646-12649; doi.org/10.1039/C6CC07552E

  5. An Fe-S cluster in the conserved Cys-rich region in the catalytic subunit of FAD-dependent dehydrogenase complexes
    Masaki Shiota, Tomohiko Yamazaki, Keiichi Yoshimatsu, Katsuhiro Kojima, Wakako Tsugawa, Stefano Ferri and Koji Sode*
    Bioelectrochemistry (2016) 112, 178-183; doi.org/10.1016/j.bioelechem.2016.01.010

  6. Review:
  7. BioCapacitor: A novel principle for biosensors
    Koji Sode*, Tomohiko Yamazaki, Inyoung Lee, Takuya Hanashi and Wakako Tsugawa
    Biosensors and Bioelectronics (2016) 76, 20-28; doi.org/10.1016/j.bios.2015.07.065

  8. Electrochemical sensing system employing fructosamine 6-kinase enables glycated albumin measurement requing no proteolytic digestion
    Miho Kameya, Wakako Tsugawa, Mayumi Yamada-Tajima, Mika Hatada, Keita Suzuki, Akane Sakaguchi-Mikami, Stefano Ferri, David C. Klonoff and Koji Sode*
    Biotechnology Journal (2016) 11 (6), 797-804; doi.org/10.1002/biot.201500442

  9. Anti-EGFR scFv tetramer (tetrabody) with a stable monodisperse structure, strong anticancer effect, and a long in vivo half-life
    Ryutaro Asano*, Noriaki Koyama, Yasuyo Hagiwara, Yosuke Masakari, Ryota Orimo, Kyoko Arai, Hiromi Ogata, Shozo Furumoto, Mitsuo Umetsu and Izumi Kumagai*
    FEBS Open Bio (2016) 6 (6), 594-602; doi.org/10.1002/2211-5463.12073

  10. Review:
    人工抗体の機能的構造形態に関する研究
    浅野 竜太郎
    生化学 (2016) 88 (4), 380-385

  11. Review:
    がん治療を目指した二重特異性抗体の開発
    浅野 竜太郎, 熊谷 泉
    細胞 (2016) 48 (4), 8-12

  12. Review:
    次世代がん治療薬を目指した低分子二重特異性抗体の開発と高機能化
    浅野 竜太郎, 熊谷 泉
    酵素工学ニュース (2016) 75, 11-14



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