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PUBLICATIONS

2018

  1. Sakurai, K.,“A Peptide-Glycolipids Interactions Probed by Retroinverso Peptide Analogues." " Chem. Pham. Bull., 2018, 66, 45-50.
  2. Komatsu, R., Yamaguchi, T,. Kobayashi, N,. Ozeki, K.“Synthesis of alkyne-tagged and biotin-tagged Sortin1 as novel photoaffinity probes."" Bioorg. Med. Chem. Lett., 2018, 28, 1562-1565      
  3. Kitamura, K., Hiroaki, I., Sakurai, K. Dan, S., Masayuki, I.,“Target Identification of Yaku'amide B and its two distinct activities against mitochondrial F0F1-ATP synthase "" J. Am. Chem. Soc., 2018, 140, 12189-12199
  4. Sakurai, K., Amane, K., Keisuke, A.,“ Design and synthesis of small molecule-conjugated photoaffinity nanoprobes for a streamlined analysis of binding protein"" Bioorg. Med. Chem. Lett., 2018, 28, 3227-3220
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2017

  1. Malabed R., Hanashima S., Murata M., Sakurai, K. “Sterol-recognition ability and membrane-disrupting activity of Ornithogalum saponin OSW-1 and usual 3-O-glycosyl saponins" " Biochim. Biophys. Acta., 2017, 1859, 2516-2525.
  2. Hiraizumi, M., Komatsu, R., Shibata, T., Ohta, Y., Sakurai, K. “Dissecting the structural basis for the intracellular delivery of OSW-1 by fluorescent probes" Org. Biomol. Chem., 2017, 15, 3568-3570.                 
  3. Sakurai K., Hiraizumi M., Isogai N., Komatsu R., Shibata T., Ohta Y., "Synthesis of a Fluorescent Photoaffinity Probe of OSW-1 by Site-Selective Acylation of an Inactive Congener and Biological Evaluation" Chem. Commun., 2017, 53, 517-520.        
         

2016

  1. Sakurai, K., Yamaguchi, T., Mizuno, S. "Design and synthesis of fluorescent glycolipid photoaffinity probes and their photoreactivity" Bioorg. Med. Chem. Lett. 2016,26, 5110-5115.                             
  2. Yamada, R., Hiraizumi, M., Narita, S., Sakurai, K. "Two-step synthesis of a clickable photoaffinity probe from an anticancer saponin OSW-1 and its photochemical reactivity" Asian. J. Org. Chem. 2016, 5, 330-334.                
  3. Sakurai, K., Hatai, Y., Okada, A. “Gold Nanoparticle-Based Multivalent Carbohydrate Probes: Selective Photoaffinity Labeling of Carbohydrate-Binding Proteins” Chem.Sci. 2016, 7, 702-706.                           

2015

  1. Sakurai, K., Ozawa, S., Yamaguchi, T. “Photoaffinity Labeling Studies of the Carbohydrate-Binding Proteins with Different Affinities”. Bioorg. Med. Chem. 2015, 23, 5319–5325.

  2. Sakurai, K., Yasui, T., Mizuno, S. “Comparative analysis of diazirine-based photoaffinity probes on their reactivity toward a carbohydrate binding protein” Asian. J. Org. Chem. 2015, 4, 724–728. Selected as a Cover Picture Article.

  3. Sakurai, K. “Photoaffinity Probes for Identification of Carbohydrate-Binding Proteins” Asian J. Org. Chem. 2015, 4, 116-126. Selected as a Very Important Paper (VIP). Also selected as a Cover Picture Article.

  4. Sakurai, K. “Photoaffinity Labeling Approaches toward Identification of Carbohydrate-Lectin Interactions” Trends Glycosci. Glycotech. 2015, 27, 1-12.

2014

  1. Sakurai, K., Takeshita, T., Hiraizumi, M., Yamada, R. “Synthesis of OSW-1 Derivatives by Site-Selective Acylation and Their Biological Evaluation” Org. Lett., 2014, 16, 6318–6321.

  2. Sakurai, K., Ozawa, S., Yamada, R., Yasui, T., Mizuno, S. “Comparison of the Reactivity of Carbohydrate Photoaffinity Probes with Different Photoreactive Groups” ChemBioChem, 2014, 15, 1399-1403. Selected as a Cover Picture Article.

  3. Yamada, R., Takeshita, T., Hiraizumi, M., Shinohe, D., Ohta, Y., Sakurai, K. “Fluorescent Analog of OSW-1 and its Cellular Localization” Bioorg. Med. Chem. Lett., 2014, 24, 1839-1842.

2013

  1. 櫻井香里「フォトアフィニティープローブシステムを用いた生物活性分子―タンパク質相互作用解析へのアプローチ」生命化学研究レター No.41 (2013 February) 9-13.

  2. Sakurai, K., Yamada, R., Okada, A., Tawa M., S. Ozawa, M., Inoue, M. “Selective Fluorescence Detection of Small-Molecule-Binding Proteins by Using a Dual Photoaffinity Labeling System” ChemBioChem. 2013, 14 421-425.

2012

  1. Sakurai, K. Tawa M., Okada, A., Yamada, R., Sato, N., Inahara, M., Inoue, M. “Active/Inactive Dual-Probe Approach to Selective Photoaffinity Labeling of Small-Molecule Binding Proteins” Chemistry-Asian J.2012, 7, 1567–1571.

2010

  1. Kleiner, R., Dumelin, C., Tiu, G., Sakurai, K., Liu, D. R. “In Vitro Selection of a DNA-Templated Small-Molecule Library Reveals a Class of Macrocyclic Kinase Inhibitors”. J. Am. Chem. Soc. 2010 132, 11779–11791.

  2. Sakurai, K., Kahne, D. “Design and Synthesis of Functionalized Trisaccharides as p53-Peptide Mimics” Tetrahedron Lett. 2010, 51, 3724-3727.

  3. Sakurai, K., Noguchi, K., Nishibe, K. “3-N-(2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-yl)-1,5-bis(4-methoxyphenyl)biuret” Acta Cryst. 2010. E66, o655.

  4. Sakurai, K., Fukumoto, T., Noguchi, K., Sato, N., Asaka, H., Moriyama, M., Yohda, M. “Three Dimensional Structures of
    OSW-1 and Its Congener” Org. Lett. 2010, 12, 5732–5735.

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~2009

  1. Sakurai, K., Liu, D. R. “DNA-Templated Organic Synthesis (DTS): A Novel Approach to the Discovery of Functional Small Molecules Based on Nature’s Evolutionary Principles” J. Synth. Org. Chem. 2008, 66(6), 590-604.

  2. Sakurai, K., Schubert, C., Kahne, D. “Crystallographic Analysis of an 8-mer p53 Peptide Analogue Complexed with MDM2” J. Am. Chem. Soc. 2006 128, 11000-11001.

  3. Sakurai, K., Snyder, T. M., Liu, D. R. “DNA-Templated Functional Group Transformations Enable Sequence-Programmed Synthesis Using Small Molecule Reagents” J. Am. Chem. Soc. 2005, 127, 1660-1661.

  4. Kanan, M.W., Rozenman, M. M., Sakurai, K., Snyder, T. M., Liu. D. R. “Reaction Discovery Enabled by DNA-Templated Synthesis and In Vitro Selection” Nature 2004, 431, 545-549.

  5. Sakurai, K., Chung, H. S., Kahne, D. “Use of a Retroinverso p53 Peptide as an Inhibitor of MDM2” J. Am. Chem. Soc. 2004, 126, 16288-16289.

  6. Gildersleeve, J., Smith, A., Sakurai, K., Raghavan, S., Kahne, D. “Scavenging Byproducts in the Sulfoxide Glycosylation Reaction: Application to the Synthesis of Ciclamycin 0” J. Am. Chem. Soc. 1999, 121, 6176-6182.
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Sakurai Laboratory

〒184-8588
東京都小金井市中町2-24-16
東京農工大学小金井キャンパス
10号館205号室