The 104th Spring Annual Meeting of the Chemical Society of Japan was held at the Nihon University, Funabashi Campus, and Kamoshita, a D2 student, gave an oral presentation.
Presentation title：Development of target protein labeling system using gold-nanoparticle probes

The 104th Spring Annual Meeting of the Chemical Society of Japan was held at the Nihon University, Funabashi Campus, and Ono Masaki, a B4 student gave a poster presentation.
Poster title：Development of a natural product functionalized gold-nanoparticle photoaffinity probe for target analysis

B4 Ono Masaki, Tanigami Kotone Sakamoto Kazutoshi gave a presentation of graduation thesis

Myat Nyein Khine, D3, received the Best Poster Award at the 28th French-Japanese Symposium on Medicinal & Fine Chemistry held on October 4, 2023. Congratulations to Khine san!

Title：Target protein analysis of anticancer saponin OSW-1

Our group has been on a molecular fishing expedition in search for target proteins of potent and selective anticancer natural product called OSW-1, which is found in the roots of an African lily. Target proteins are key proteins that mediate a mechanism of action of drug molecules. Using a molecular fishing rod, which is a chemically modified natural product with a tag, I narrowed down a list of candidate proteins we found earlier and uncovered a potential target protein. I then investigated whether OSW-1 and the protein actually bind with an acceptable target-like strength. I am currently confirming the role of this protein in the anticancer mechanism of OSW-1, aiming to discover a novel anticancer therapeutic pathway with little to no side effects. Identifying an elusive target of OSW-1 and therefore the mechanism of action, should lead to the development of novel selective anticancer drugs.

See Tokyo University of Agriculture and Technology website for details.

See WISE-TUAT program in Tokyo University of Agriculture and Technology.

French-Japanese Symposium on Medicinal&Fine Chemistry

M2 student Kotaro Abe gave an oral presentation at the 84th Kanto Regional Symposium of The Society of Synthetic Organic Chemistry, Japan held at TUAT.

D2 student Myatnyein Khine, M2 student Ayaka Tsuruno gave oral presentations and M1 student Riko Sueki a poster presentation at the 103th Annual Meeting of The Chemistry Society of Japan held at Tokyo Science University, Noda Campus.

D2 student Myatnyein Khine presented a poster at Future Drug Discovery Empowered by Chemical Biology Symposium (ChemBioNara2023) held in Nara.

D1 student Kaysa Faradis Mahira won Best Student Presentation Award at The 14 th Annual Meeting of the Society of Japanese Women Scientists on line, which was organized by the Society of Japanese Women Scientists Poster title：The Role of Oxysterol Binding Protein Related Family Proteins in the Anticancer Activity of Steroidal Saponin OSW 1

Dr. Sasaki of Daiichi Sankyo RD Novare Co. visited TUAT to give a lecture in "Advanced Biotechnology Business" in the Department of Biotechnology and Life Science.

Kotaro Abe presented posters at the 39th Medicinal Chemistry Symposium on line.

M1 Turuno ayaka presented posters at the 16th Japan Chemical Biology Society at Toyama.
Poster title：Development of new electrophilic gold-nanoparticle probes for affinity labeling of target proteins

Sakurai received the Society of Japanese Women Scientists Award for "Development of target protein identification methods for natural products and elucidation of their mechanisms of action" and gave a lecture at the SJWS's award reception online on 22 May. The award plaque and the prize were presented to Sakurai at the award ceremony at TUAT on 30 May by Prof. Junko Atomi, President of SWJS, and Director Miho Shimizu in the presence of President Chiba and Dean Nakamura of the Graduate School of Engineering.
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