MEMBERS田中・新垣研究室

新垣 篤史教授

居室：11号館304
TEL ：042-388-7320

所属：
大学院工学研究院生命機能科学部門
主な研究テーマ：
  • 磁性細菌の磁気微粒子合成機構の解析
  • 甲虫表皮形成機構の解析
  • 生体硬組織に由来する生体分子を利用した材料開発

経歴

  • 2003.3東京農工大学大学院工学研究科生命工学専攻　博士後期課程修了・学位取得（博士(工学)）
  • 2003.4-2004.3早稲田大学理工学研究科・客員研究助手
  • 2004.4-2005.3早稲田大学理工学研究科・日本学術振興会特別研究員(PD)
  • 2005.4-2011.10東京農工大学大学院共生科学技術研究院・助手（2007年より大学院共生科学技術研究院・助教、2010年より大学院工学研究院・助教）
  • 2011.11-2021.7東京農工大学大学院工学研究院・准教授
  • 2021.8-現在東京農工大学大学院工学研究院・教授

所属学会

日本化学会、日本生物工学会、マリンバイオテクノロジー学会、電気化学会

論文

  1. Ryoto Tomoe, Kazushi Fujimoto, Tsuyoshi Tanaka, Atsushi Arakaki, David Kisailus, Tomoko Yoshino "Lipid Membrane Modulated Control of Magnetic Nanoparticles within Bacterial Systems."J. Biosci. Bioeng. (2023)
  2. Wei Huang, Devis Montroni, Taifeng Wang, Satoshi Murata, Atsushi Arakaki, Michiko Nemoto, and David Kisailus, "Nanoarchitected tough biological composites from assembled chitinous scaffolds." Acc. Chem. Res., 55 (10), 1360-1371 (2022)
  3. Kosuke Arai, Satoshi Murata, Taifeng Wang, Wataru Yoshimura, Mayumi Oda-Tokuhisa, Tadashi Matsunaga, David Kisailus, Atsushi Arakaki, "Adsorption of Biomineralization Protein Mms6 on Magnetite (Fe3O4) Nanoparticles" International Journal of Molecular Sciences.,23 (10) 5554 (2022)
  4. Tomoko Yoshino, Yihao Mao, Yoshiaki Maeda, Ryo Negishi, Satoshi Murata, Seiichiro Moriya, Hirofumi Shimada, Atsushi Arakaki, Kenichi Kobayashi, Yoshitsugu Hagiwara, Kazutoshi Okamoto, Tsuyoshi Tanaka, "Single-cell genotyping of phytoplankton from ocean water by gel-based cell manipulation." Biotechnol. J., e2100633. (2022)
  5. Taifeng Wang, Wei Huang, Cong Huy Pham, Satoshi Murata, Steven Herrera, Nathan D. Kirchhofer, Bassim Arkook, Dejan Stekovic, Mikhail E. Itkis, Nir Goldman, Luis Zepeda-Ruiz, Mikhail Zhernekov, Michiko Nemoto, Atsushi Arakaki, David Kisailus, "Mesocrystalline Ordering and Phase Transfromation of Iron Oxide Biominerals in the Ultrahard Teeth of Cryptochiton stelleri" small structures, (2022)
  6. Satoshi Murata, Jesus Rivera, Mi Yong Noh, Naoya Hiyoshi, Wen Yang, Diworth Y. Parkinson, Harold S Barnard, Yasuyuki Arakane, David Kisailus, Atsushi Arakaki, "Unveiling characteristic proteins for the structural development of beetle elytra" Acta Biomater., 140, 467-480 (2022)
  7. Jesus Rivera, Satoshi Murata, Maryam Sadat Hosseini, Alison Pickle, Adwait A Trikanad, Wen Yang, Nana Matsumoto, Dilworth Y. Parkinson, Harold S. Barnard, Pablo Zavattieri, Atsushi Arakaki, David kisailus "Structural Design Variations in Beetle Elytra."Adv.Funct. Mater.,, 2106468, (2021)
  8. Atsushi Arakaki, Takuya Matsumoto, Nobumitsu Shimura, Yoshiaki Maeda, Tomoko Yoshino, Mitsufumi Matsumoto, David Kisailus, Tsuyoshi Tanaka "Analysis of UV Irradiation-Induced Cell Settling of an Oleaginous Diatom, Fistulifera Solaris, for Efficient Biomass Recovery"Algal. Res. 47, 101834 (2020)
  9. Anna Pohl, Steven A. Herrera, David Restrepo, Ryo Negishi, Jae-Young Jung, Chris Salinas, Richard Wuhrer,  Tomoko Yoshino, Joanna McKittrick, Atsushi Arakaki, Michiko Nemoto, Pablo Zavattieri, David Kisailus "Radular Stylus of Cryptochiton Stelleri: A Multifunctional Lightweight and Flexible Fiber-Reinforced Composite”J. Mech. Behav. Biomed. Mater., 111, 103991, (2020)
  10. Giulia Mirabello, Alessandro Ianiro, Paul H. H. Bomans, Takuto Yoda, Atsushi Arakaki, Heiner Friendrich, Gijsbertus de With and Nico A. J. M. Sommerdijk "Crystallization by Particle Attachment is a Colloidal Assembly Process"Nat. Mater., 4 (19), 391-396, (2020)
  11. Atsushi Arakaki, Mayu Goto, Mina Maruyama, Takuto Yoda, Masayoshi Tanaka, Ayana Yamagishi, Yasuo Yoshikuni, Tadashi Matsunaga "Restoration and Modification of Magnetosome Biosynthesis by Internal Gene Acquisition in a Magnetotactic Bacterium"Biotechnol J., 15, 2000278, (2020)
  12. Taifeng Wang, Atsushi Arakaki, David Kisailus "Template-free Synthesis of Ta3N5 Hollow Nanospheres as a Visible-light-driven Photocatalyst"J. Phys. Commun., 3, 075010 (2019)
  13. Masayoshi Tanaka, Thanawat Suwatthanarak, Atsushi Arakaki, Benjamin R. G. Johnson, Stephen D. Evans, Mina Okochi, Sarah S. Staniland, Tadashi Matsunaga "Enhanced Tubulation of Liposome Containing Cardiolipin by MamY Protein from Magnetotactic Bacteria" Biotechnol. J., e1800087 (2018)
  14. Tsuyoshi Tanaka, Osamu Nogariya, Nozomi Shionoiri, Yoshiaki Maeda, Atsushi Arakaki "Integrated Molecular Analysis of the Inactivation of a Non-enveloped Virus, Feline Calicivirus, by UV-C Radiation" J. Biosci. Bioeng., 126, 63-68 (2018)
  15. Atsushi Arakaki, Shintaro Nakata, Takahito Tokuhisa, Yuta Ogawa, Katsuhiko Sato, Takehiro Sonoi, Stuart P Donachie, Tadashi Matsunaga "Quantitative and Time-course Analysis of Microbial Degradation of 1H,1H,2H,2H,8H,8H-perfluorododecanol in Activated Sludge" Appl. Microbiol. Biotechnol., 101, 8259-8266 (2017)
  16. Atsushi Arakaki, Takuya Matsumoto, Takuma Tateishi, Mitsufumi Matsumoto, Daisuke Nojima, Yoshino Tomoko, Tsuyoshi Tanaka "UV-C Irradiation Accelerates Neutral Lipid Synthesis in the Marine Oleaginous Diatom Fistulifera solaris" Bioresour. Technol., 245, 1520-1526 (2017)
  17. Ayana Yamagishi, Kaori Narumiya, Masayoshi Tanaka, Tadashi Matsunaga, Atsushi Arakaki "Core Amino Acid Residues in the Morphology-Regulating Protein, Mms6, for Intracellular Magnetite Biomineralization" Sci. Rep., 6, 35670 (2016)
  18. Atsushi Arakaki, Daiki Kikuchi, Masayoshi Tanaka, Ayana Yamagishi, Takuto Yoda, Tadashi Matsunaga "Comparative Subcellular Localization Analysis of Magnetosome Proteins Reveals a Unique Localization Behavior of Mms6 Protein onto Magnetite Crystals" J. Bacteriol., 198, 2794-2802 (2016)
  19. Ayana Yamagishi, Masayoshi Tanaka, Jos J. M. Lenders, Jarla Thiesbrummel, Nico A. J. M. Sommerdijk, Tadashi Matsunaga, Atsushi Arakaki Control of Magnetite Nanocrystal Morphology in Magnetotactic Bacteria by Regulation of mms7 Gene Expression" Sci. Rep., 6, 29785 (2016)
  20. Masayoshi Tanaka, William Knowles, Rosemary Brown, Nicole Hondow, Atsushi Arakaki, Stephen Baldwin, Sarah Staniland, Tadashi Matsunaga "Biomagnetic Recovery of Selenium: Bioaccumulating of Selenium Granules in Magnetotactic Bacteria" Appl. Environ. Microbiol., 82, 3886-3891 (2016)
  21. Atsushi Arakaki, Mami Takahashi, Masahito Hosokawa, Tadashi Matsunaga, Tsuyoshi Tanaka "Bacterial Inactivation by Applying an Alternating Electromagnetic Field Using PAMAM Dendron-modified Magnetic Nanoparticles" Electrochemistry, 84, 324–327 (2016)
  22. Takahito Tokuhisa, Masashi Kawasaki, David Kisailus, Masamichi Yuda, Tadashi Matsunaga, Atsushi Arakaki "Crystal Growth of Aspirin Using a Temperature-Controlled Microfluidic Device" Cryst. Growth Des., 15, 4549-4555 (2015)
  23. Jos J.M. Lenders, Harshal R. Zope, Ayana Yamagishi, Paul H.H. Bomans, AtsushAtsushi Arakakii Arakaki A, Alexander Kros, Gijsbertus de With, Nico A.J.M. Sommerdijk "Bioinspired Magnetite Crystallization Directed by Random Copolypeptides" Adv. Funct. Mater., 25, 711-719 (2015)
  24. Atsushi Arakaki, Katsuhiko Shimizu, Mayuimi Oda, Takeshi Sakamoto, Tatsuya Nishimura, Takashi Kato "Biomineralization-inspired synthesis of functional organic/inorganic hybrid materials: organic molecular control of self-organization of hybrids" Org. Biomol. Chem., 13, 974-989 (2015)
  25. Arihiro Kanazawa, Kotaro Satoh, Shokyoku Kanaoka, Masato Kakihana, Makoto Kobayashi, Junki Sato, Hiroaki Imai, Yuya Oaki, Atsushi Arakaki, Kiyofumi Katagiri, Masami Kamigaito, Sadahito Aoshima "Controlled Radical Polymerization of Styrene with Magnetic Iron Oxides Prepared through Hydrothermal, Bioinspired, and Bacterial Processes" RSC Adv., 5, 51122-51129 (2015)
  26. Jos J.M. Lenders, Cem L. Altan, Paul H.H. Bomans, Atsushi Arakaki, Seyda Bucak, Gijsbertus de With, Nico A.J.M. Sommerdijk "A Bioinspired Coprecipitation Method for the Controlled Synthesis of Magnetite Nanoparticles" Cryst. Growth Des., 14, 5561-5568 (2014)
  27. Atsushi Arakaki, Ayana Yamagishi, Ayumi Fukuyo, Masayoshi Tanaka, Tadashi Matsunaga "Co‐ordinated Functions of Mms Proteins Define the Surface Structure of Cubo‐octahedral Magnetite Crystals in Magnetotactic Bacteria" Mol. Microbiol., 93, 554-567 (2014)
  28. Tsukasa Takamura, Tatsuya Tashiro, Atsushi Arakaki, Adarsh Sandhu "Functionalization of Magnetotactic Bacteria for Microrobotic Applications" IEEE Trans. Magnet., 50 (2014)
  29. Atsushi Arakaki, Daisuke Iwama, Yue Liang, Nagisa Murakami, Masaharu Ishikura, Tsuyoshi Tanaka, Tadashi Matsunaga "Glycosylceramides from Marine Green Microalga Tetraselmis sp." Phytochemistry, 85. 107-114 (2013)
  30. Daisuke Baba, Yasuhiro Seiko, Takuya Nakanishi, Hong Zhang, Atsushi Arakaki, Tadashi Matsunaga, Tetsuya Osaka "Effect of Magnetite Nanoparticles on Living Rate of MCF-7 Human Breast Cancer Cells" Colloids Surf. B: Biointerfaces., 95. 254-257 (2012)
  31. Arihiro Kanazawa, Shokyoku Kanaoka, Naoki Yagita, Yuya Oaki, Hiroaki Imai, Mayumi Oda, Atsushi Arakaki, Tadashi Matsunaga, Sadahito Aoshima "Biologically Synthesized or Bioinspired Process-Derived Iron Oxides as Catalysts for Living Cationic Polymerization of Vinyl Ether" Chem. Commun. (Camb.), 48. 10904-10906 (2012)
  32. Tsuyoshi Tanaka, Keiyu Shibata, Masahito Hosokawa, Keiichi Hatakeyama, Hideyuki Gomyo, Atsushi Arakaki, Takeyuki Mogi, Tomoyuki Taguchi, Hitoshi Wake, Takeo Tanaami, Tadashi Matsunaga "Characterization of Magnetic Nanoparticles Modified with Thiol Core, Functionalized PAMAM Dendron for DNA Recovery" J. Colloid Interface. Sci., 377. 469-475 (2012)
  33. Atsushi Arakaki, Keiyu Shibata, Takeyuki Mogi, Masahito Hosokawa, Keiichi Hatakeyama, Hideyuki Gomyo, Tomoyuki Taguchi, Hitoshi Wake, Takeo Tanaami, Tadashi Matsunaga, Tsuyoshi Tanaka "Efficient DNA Release from PAMAM Dendrimer-Modified Superparamagnetic Nanoparticles for DNA Recovery" Polym. J., 44. 672-677 (2012)
  34. Masayoshi Tanaka, Eri Mazuyama, Atsushi Arakaki, Tadashi Matsunaga "Mms6 Protein Regulates Crystal Morphology During Nano-Sized Magnetite Biomineralization In Vivo" J. Biol. Chem., 286. 6386-6392 (2011)
  35. Johanna M Galloway, Atsushi Arakaki, Fukashi Masuda, Tsuyoshi Tanaka, Tadashi Matsunaga, Sarah S Staniland "Magnetic Bacterial Protein Mms6 Controls Morphology, Crystallinity and Magnetism of Cobalt-doped Magnetite Nanoparticles In Vitro" J. Mater. Chem. B Mater. Biol. Med. , 21. 15244-15254 (2011)
  36. Mitsufumi Matsumoto, Daisuke Iwama, Atsushi Arakaki, Akira Tanaka, Tsuyoshi Tanaka, Hideaki Miyashita, Tadashi Matsunaga "Altererythrobacter Ishigakiensis sp. nov., an Astaxanthin-Producing Bacterium Isolated from Marine Sediments" Int. J. Syst. Evol. Microbiol., 61. 2956-2961 (2011)
  37. Masayoshi Tanaka, Atsushi Arakaki, Tadashi Matsunaga "Identification and Functional Characterization of Liposome Tubulation Protein from Magnetotactic Bacteria" Mol. Microbiol., 76. 480-488 (2010)
  38. Atsushi Arakaki, Fukashi Masuda, Yosuke Amemiya, Tsuyoshi Tanaka, Tadashi Matsunaga "Control of the Morphology and Size of Magnetite Particles with Peptides Mimicking the Mms6 Protein from Magnetotactic Bacteria" J. Colloid Interface. Sci., 343. 65-70 (2010)
  39. Atsushi Arakaki, Mie Shibusawa, Masahito Hosokawa, and Tadashi Matsunaga "Preparation of Genomic DNA from a Single Species of Uncultured Magnetotactic Bacterium by Multiple Displacement Amplification" Appl. Environ. Microbiol., 76. 1480-1485 (2010)
  40. Atsushi Arakaki, Kaori Ooya, Yasuto Akiyama, Masahito Hosokawa, Masaru Komiyama, Akira Iizuka, Ken Yamaguchi, Tadashi Matsunag "TCR-β Repertoire Analysis of Antigen-Specific Single T Cells Using a High-Density Microcavity Array" Biotechnol. Bioeng., 106. 311-318 (2010)
  41. Atsushi Arakaki, Yuko Ishii, Takahito Tokuhisa, Seiichiro Murata, Katsuyuki Sato, Takehiro Sonoi, Haruyoshi Tatsu, Tadashi Matsunaga "Microbial Biodegradation of a Novel Fluorotelomer Alcohol, 1H,1H,2H,2H,8H,8H-Perfluorododecanol, Yields Short Fluorinated Acids" Appl. Microbiol. Biotechnol., 88. 1193-1203 (2010)
  42. Masahito Hosokawa, Taishi Hayata, Yorikane Fukuda, Atsushi Arakaki, Tomoko Yoshino, Tsuyoshi Tanaka, Tadashi Matsunaga "Size-Selective Microcavity Array for Rapid and Efficient Detection of Circulating Tumor Cells" Anal. Chem., 82. 6629-6635 (2010)
  43. Masayoshi Tanaka, Atsushi Arakaki, Sarah S Staniland, Tadashi Matsunaga "Simultaneously Discrete Biomineralization of Magnetite and Tellurium Nanocrystals in Magnetotactic Bacteria" Appl. Environ. Microbiol., 76. 5526-5532 (2010)
  44. Hidekazu Nakazawa, Atsushi Arakaki, Sachiko Narita-Yamada, Isao Yashiro, Koji Jinno, Natsuko Aoki, Ai Tsuruyama, Yoshiko Okamura, Satoshi Tanikawa, Nobuyuki Fujita, Haruko Takeyama, Tadashi Matsunaga "Whole Genome Sequence of Desulfovibrio magneticus Strain RS-1 Revealed Common Gene Clusters in Magnetotactic Bacteria" Genome Res., 19, 1801-1808 (2009)
  45. Tadashi Matsunaga, Michiko Nemoto, Atsushi Arakaki, Masayoshi Tanaka "Proteomic Analysis of Irregular Bullet-Shaped Magnetosomes in the Sulfate- Reducing Bacterium Desulfovibrio magneticus RS-1" Proteomics, 9, 3341-3352 (2009)
  46. Masahito Hosokawa, Atsushi Arakaki, Masayuki Takahashi, Tetsushi Mori, Haruko Takeyama, Tadashi Matsunaga "High-Density Microcavity Array for Cell Detection: Single-Cell Analysis of Hematopoietic Stem Cells in Peripheral Blood Mononuclear Cells"Anal. Chem., 81, 5308-5313 (2009)
  47. Tadashi Matsunaga, Masahito Hosokawa, Atsushi Arakaki, Tomoyuki Taguchi, Tetsushi Mori, Tsuyoshi Tanaka, Haruko Takeyama "High-Efficiency Single-Cell Entrapment and Fluorescence in Situ Hybridization Analysis Using a Poly(dimethylsiloxane) Microfluidic Device Integrated with a Black Poly(ethylene terephthalate) Micromesh" Anal. Chem., 80, 5139-5145 (2008)
  48. Sho Hideshima, Masahiro Yanagisawa, Atsushi Arakaki, Tadashi Matsunaga, Tetsuya Osaka "Quantitative Detection of Immunoreaction Using Magnetite Nanoparticles and Raman Scatterintg Spectroscopy" e-J. Surf. Sci. Nanotechnol., 6, 142-146 (2008)
  49. Takeyuki Suzuki, Yoshiko Okamura, Atsushi Arakaki, Haruko Takeyama, Tadashi Matsunaga "Cytoplasmic ATPase　Involved in Ferrous Ion Uptake from Magnetotactic Bacterium Magnetospirillum magneticum AMB-1" FEBS Lett., 581, 3443-3448 (2007)
  50. Tomoyuki Taguchi, Atsushi Arakaki, Haruko Takeyama, Satoshi Haraguchi, Masato Yoshino, Masao Kaneko, Yoshio Ishimori, Tadashi Matsunaga "Detection of Cryptosporidium parvum Oosysts Using a Microfluidic Device Equipped with the SUS Micromesh and FITC-Labeled Antibody" Biotechnol. Bioeng., 96, 272-280 (2007)
  51. Yosuke Amemiya, Atsushi Arakaki, Sarah S. Staniland, Tsuyoshi Tanaka, Tadashi Matsunaga "Controlled Formation of Magnetite Crystal by Partial Oxidation of Ferrous Hydroxide in the Presence of Recombinant Magnetotactic Bacterial Protein Mms6" Biomaterials, 28, 5381-5389 (2007)
  52. Masayoshi Tanaka, Yoshiko Okamura, Atsushi Arakaki, Tsuyoshi Tanaka, Haruko Takeyama, Tadashi Matsunaga "Origin of Magnetosome Membrane Proteomic Analysis of Magnetosome Membrane and Comparison with Cytoplasmic Membrane" Proteomics, 6, 5234-5247 (2006)
  53. Atsushi Arakaki, John Webb, Tadashi Matsunaga, “A novel protein tightly bound to bacterial magnetic particles in Magnetospirillum magneticum strain AMB-1”, J. Biol. Chem., 278, 8745-8750 (2003).

著書

  1. Atsushi Arakaki、Masayoshi Tanaka、Tadashi Matsunaga「Molecular Mechanism of Magnetic Crystal Formation in Magnetotactic Bacteria」"Biological Magnetic Materials and Applications" springer pp23-51 (2018)
  2. 新垣 篤史、山岸 彩奈、松永 是「第5章　第1節　磁性細菌の磁気微粒子形態制御機構の解析と磁性材料合成への応用」"生物模倣技術と新材料・新製品開発への応用" 技術情報協会 pp325-330 (2014)
  3. 新垣 篤史、山岸 彩奈、松永 是「第3章　3.3.3　磁性細菌の機能を利用した磁性材料の合成技術」"地球を救うメタルバイオテクノロジー" 成山堂書店 pp162-170 (2014)
  4. Atsushi Arakaki、Michiko Nemoto、Tadashi Matsunaga「Chapter 10. Molecular Bioengineering of Magnetosomes for Biotechnological Applications」"Coordination Chemistry in Protein Cages: Principles, Design, and Applications" Wiley pp241-266 (2013)
  5. 新垣 篤史、松永 是「第4章-10 細胞分離技術を用いたがん特異的免疫細胞の遺伝子スクリーニング法の開発」"磁性ビーズのバイオ・環境技術への応用展開" CMC出版 (2010)
  6. 新垣 篤史、松永 是「バイオミネラリゼーション」"ナノバイオ大事典" 株式会社テクノシステム pp424-427 (2007)
  7. 新垣 篤史、松永 是"一細胞定量解析の最前線－ライフサーベイヤ構築に向けて" CMC出版 pp267-272 (2006)
  8. Atsushi Arakaki「Molecular Bioengineering of Bacterial Magnetic Particles for Biotechnological Applications」"Magnetoreception and Magnetosomes in Bacteria" springer pp227-254 (2006)
  9. 新垣 篤史、鈴木 健之「バクテリアの合成するナノ磁性ビーズの応用技術」"磁性ビーズのバイオ・環境技術への応用展開" CMC出版 pp78-85 (2006)

解説・総説等

  1. A. Arakaki, K. Shimizu, M. Oda, T. Sakamoto, T. Nishimura, T. Kato, “Biomineralization-inspired synthesis of functional organic/inorganic hybrid materials: organic molecular control of self-organization of hybrids”, Org. Biomol. Chem., 13, 974-989 (2015).
  2. A. Arakaki, H. Nakazawa, M. Nemoto, T. Mori, T. Matsunaga, “Formation of magnetite by bacteria and its application”, J. R. Soc. Interface, 5, 977-999 (2008).

招待講演/依頼講演等