Amine Catalyst
VCD Spectroscopy Distinguishes the Enamine and Iminium Ion of a 1,1'-Binaphthyl Azepine
Golub, T. P.; Kano, T.; Maruoka, K.; Merten, C. Chem. Commun. 2022, 58, 8412-8415.
DOI: 10.1039/D2CC02863HPUBLICATIONS
2021-2022
Amine Catalyst
Design and Synthesis of Phenylcyclopropane-Based Secondary Amine Catalysts and Their Applications in Asymmetric Reactions
Takeshima, A.; Kano, T. Synlett. 2022, 33, 1778-1787.
DOI: 10.1055/a-1796-7387
Sulfur Chirality
Practical Asymmetric Synthesis of Chiral Sulfoximines via Sulfur-Selective Alkylation
Maeda, Y.; Hamada, S.; Aota, Y. Otsubo, K.; Kano, T.; Maruoka, K. J. Org. Chem. 2022, 87, 3652-3660
DOI: 10.1021/acs.joc.1c02424
Amine Catalyst
Design and Synthesis of Phenylcyclopropane-based Chiral Amine Catalysts and Their Application in Asymmetric Reactions
Homma, C.; Kano, T. J. Synth. Org. Chem. Jpn. 2022, 80, 92-102
Alkylsilyl Peroxide
Ni-Catalyzed C(sp2)−H Alkylation of N-Quinolylbenzamide Using Alkylsilyl Peroxides as Structurally Diverse Alkyl Sources
Tsuzuki, S.; Sakurai, S.; Matsumoto, A.; Kano, T.; Maruoka, K. Chem. Commun. 2021, 57, 7942-7945
Amine Catalyst
Synthesis of Alkynyl Z-Ketimines and Their Application in Amine-catalyzed Asymmetric Mannich Reactions and Conjugate Addition
Homma, C.; Yamanaka, M.; Kano, T.; Maruoka, K. Tetrahedron 2021, 91, 132225
Amine Catalyst
Bifunctional Amino Sulfonamide-catalyzed Asymmetric Conjugate Addition to Alkenyl Alkynyl Ketimines as Enone Surrogates
Homma, C.; Kano, T.; Maruoka, K. Chem. Commun. 2021, 57, 2808-2811
DOI: 10.1039/D0CC07842E
PTC
Asymmetric α-Hydroxylation of α-Aryl-δ-lactams with Molecular Oxygen under Phase-Transfer Conditions
Inukai, T.; Kano, T.; Maruoka, K. Org. Lett. 2021, 23, 792-796
Amine Catalyst
Construction of Chiral α-tert-Amine Scaffolds via Amine-catalyzed Asymmetric Mannich Reactions of Alkyl-substituted Ketimines
Homma, C.; Kano, T.; Maruoka, K. Chem. Sci. 2021, 12, 1445-1450
DOI: 10.1039/D0SC05269H
Alkylsilyl Peroxide
Cu-catalyzed O-Alkylation of Phenol Derivatives with Alkylsilyl Peroxides
Sakurai, S.; Kano, T.; Maruoka, K. Chem. Commun. 2021, 57, 81-84
DOI: 10.1039/d0cc07305a
1997-2020
106. CuCl2-Mediated Oxidative Intramolecular α-Arylation of Ketones with Phenolic Nucleophiles via Oxy-Allyl Cation Intermediates
Mochimatsu, T.; Aota, Y.; Kano, T.*; Maruoka, K.* Chem.–Asian J. 2020, 15, 3816-3819.
105. Cu-Catalyzed Enantioselective Alkylarylation of Vinylarenes Enabled by Chiral Binaphthyl-BOX Hybrid Ligands
Sakurai, S.; Matsumoto, A.; Kano, T.; Maruoka, K.* J. Am Chem. Soc. 2020, 142, 19017-19022. (Cover Picture)
104. Synthesis of Electron-Deficient Chiral Biphenols and Their Applications in Catalytic Asymmetric Reactions
Yasumoto, K.; Kano, T.*; Maruoka, K.* J. Org. Chem. 2020, 85, 10232-10239.
103. Organocatalytic Formal (3 + 2) Cycloaddition toward Chiral Pyrrolo[1,2‑a]indoles via Dynamic Kinetic Resolution of Allene Intermediates
Bai, J.-F.; Zhao, L.; Wang, F.; Yan, F.; Kano, T.; Maruoka, K.; Li, Y.* Org. Lett. 2020, 22, 5439-5445.
102. Development of Ketone-Based Brominating Agents (KBA) for the Practical Asymmetric α-Bromination of Aldehydes Catalyzed by Tritylpyrrolidine
Takeshima, A.; Shimogaki, M.; Kano, T.*; Maruoka, K.* ACS Catal. 2020, 10, 5959-5963.
101. Enantioselective Synthesis of Monosaccharide Analogues by Two-step Sequential Enamine Catalysis: Benzoyloxylation and Aldol Reaction
Shimogaki, M.; Takeshima, A.; Kano, T.*; Maruoka, K.* Eur. J. Org. Chem. 2020, 2028-2032. (Cover Picture)
100. Brønsted Acid-Catalyzed Intramolecular α-Arylation of Ketones with Phenolic Nucleophiles via Oxy-Allyl Cation Intermediates
Aota, Y.; Doko, Y.; Kano, T.*; Maruoka, K.* Eur. J. Org. Chem. 2020, 1907-1911. (Selected as a VIP paper)
99. Construction of a Quaternary Carbon Center by Catalytic Asymmetric Alkylation of 3-Arylpiperidin-2-ones under Phase-Transfer Conditions
Inukai, T.; Kano, T.*; Maruoka, K.* Angew. Chem., Int. Ed. 2020, 59, 2211-2214. (Cover Picture)(Highlighted in SYNFACTS, 2020, 214)
98. Asymmetric Synthesis of Chiral Sulfoximines via the S-Arylation of Sulfinamides
Aota, Y.; Kano, T.*; Maruoka, K.* J. Am. Chem. Soc. 2019, 141, 19263-19268.
97. Efficient Synthesis of Cyclic Sulfoximines from N-Propargylsulfinamides through Sulfur–Carbon Bond Formation
Aota, Y.; Maeda, Y.; Kano, T.*; Maruoka, K.* Chem.–Eur. J. 2019, 25, 15755-15758.
96. Asymmetric Synthesis of Chiral Sulfoximines through the S-Alkylation of Sulfinamides
Aota, Y.; Kano, T.*; Maruoka, K.* Angew. Chem., Int. Ed. 2019, 58, 17661-17665.
95. Synthesis of Phenylcyclopropane-Based Secondary Amine Catalysts and Their Applications in Enamine Catalysis
Takeshima, A.; Kano, T.*; Maruoka, K.* Org. Lett. 2019, 21, 8071-8074.
94. Asymmetric Synthesis of Chiral 1,4-Enynes through Organocatalytic Alkenylation of Propargyl Alcohols with Trialkenylboroxines
Bai, J.-F.; Yasumoto, K.; Kano, T.*; Maruoka, K.* Angew. Chem., Int. Ed. 2019, 58, 8898-8901. (Highlighted in SYNFACTS, 2019, 798)
93. One-Pot Synthesis of Less Accessible N-Boc-Propargylic Amines through BF3 Catalyzed Alkynylation and Allylation Using Boronic Esters
Yasumoto, K.; Kano, T.*; Maruoka, K.* Org. Lett. 2019, 21, 3214-3217.
92. Synthesis of 1-Aminoindenes through Aza-Prins-Type Cyclization
Bai, J.-F.; Yasumoto, K.; Kano, T.*; Maruoka, K.* Chem.–Eur. J. 2018, 24, 10320-10323.
91. BF3-Catalyzed Synthesis of Cyclic Carbamates from Boc-Protected Aminals and Alkynes
Kano, T.*; Yasumoto, K.; Maruoka, K.* Asian J. Org. Chem. 2018, 7, 1575-1578.
90. Catalyst-Controlled Diastereoselectivity Reversal in the Formation of Dihydropyrans
Kano, T.*; Maruyama, H.; Homma, C.; Maruoka, K.* Chem. Commun. 2018, 54, 3496-3499.
89. Chiral Amine-Catalyzed Asymmetric Conjugate Addition of Aldehydes to α-Phenylselenoenones as Formal Z-Allylating Agents
Kano, T.*; Maruyama, H.; Homma, C.; Maruoka, K.* Chem. Commun. 2018, 54, 176-179.
88. Asymmetric Synthesis of Less Accessible α-Tertiary Amines from Alkynyl Z-Ketimines
Kano, T.*; Aota, Y.; Maruoka, K.* Angew. Chem., Int. Ed. 2017, 56, 16293-16296. (Highlighted in SYNFACTS, 2018, 185)
87. Synthesis of Chiral Tritylpyrrolidine Derivatives and Their Application to Asymmetric Benzoyloxylation
Shimogaki, M.; Maruyama, H.; Tsuji, S.; Homma, C.; Kano, T.*; Maruoka, K.* J. Org. Chem. 2017, 82, 12928-12932.
86. Catalyst-Controlled, Enantioselective, and Diastereodivergent Conjugate Addition of Aldehydes to Electron-Deficient Olefins
Kan, S. B. J.; Maruyama, H.; Akakura, M.; Kano, T.*; Maruoka, K.* Angew. Chem., Int. Ed. 2017, 56, 9487-9491. (Highlighted in SYNFACTS, 2017, 985)
85. In Situ Generation of N-Boc-Protected Alkenyl Imines: Controlling the E/Z Geometry of Alkenyl Moieties in the Mukaiyama–Mannich Reaction
Bai, J.-F.; Sasagawa, H.; Yurino, T.; Kano, T.*; Maruoka, K.* Chem. Commun. 2017, 53, 8203-8206.
84. In Situ Generation of Less Accessible Boc-imines from Aldehydes: Construction of a Quaternary Carbon by the Mannich Reaction or Unprecedented Aldol Reaction
Kano, T.*; Homma, C.; Maruoka, K.* Org. Biomol. Chem. 2017, 15, 4527-4530. (Highlighted in SYNFACTS, 2017, 873)
83. Rate Acceleration of Solid-Liquid Phase-Transfer Catalysis by Rotor-Stator Homogenizer
Kano, T.; Aota, Y.; Maruoka, K.* Adv. Synth. Catal. 2016, 358, 2996-2999.
82. N-Boc-Aminals As Easily Accessible Precursors for Less Accessible N-Boc-Imines: Facile Synthesis of Optically Active Propargylamine Derivatives Using Mannich-Type Reactions
Yurino T.; Aota, Y.; Asakawa, D.; Kano, T.; Maruoka, K.* Tetrahedron 2016, 72, 3687-3700.
81. Synthesis of N-Boc-Propargylic and Allylic Amines by Reaction of Organomagnesium Reagents with N-Boc-Aminals and Their Oxidation to N-Boc-Ketimines
Kano, T.; Kobayashi, R.; Maruoka, K.* Org. Lett. 2016, 18, 276-279. (Highlighted in SYNFACTS, 2016, 292)
80. Brønsted Acid-catalysed Mannich Reaction Through Dual Activation of Aldehydes and N-Boc-Imines
Kano, T.; Aota, Y.; Asakawa, D.; Maruoka, K.* Chem. Commun. 2015, 51, 16472-16474. (Cover Picture)
79. Regioselectivity Switch in Chiral Amine-catalysed Asymmetric Addition of Aldehydes to Reactive Enals
Kano, T.; Maruyama, H.; Sakamoto, R.; Maruoka, K.* Chem. Commun. 2015, 51, 10062-10065.
78. Regio- and Stereoselective Conjugate Addition of Aldehydes to β-Tosyl Enones under the Catalysis of a Binaphthyl-Modified Chiral Amine
Kano, T.; Sugimoto, H.; Maruyama, H.; Maruoka, K.* Angew. Chem., Int. Ed. 2015, 54, 8462-8465. (Highlighted in SYNFACTS, 2015, 986)
77. Versatile In Situ Generated N-Boc-Imines: Application to Phase-Transfer-Catalyzed Asymmetric Mannich-Type Reactions
Kano, T.; Kobayashi, R.; Maruoka, K.* Angew. Chem., Int. Ed. 2015, 54, 8471-8474. (Highlighted in SYNFACTS, 2015, 987)
76. Design and Synthesis of a Biphenyl-based Chiral Amino Sulfonamide with High Catalytic Performance in Mannich Reactions
Kano, T.; Maruyama, H.; Akiyama, K.; Maruoka, K.* Tetrahedron Lett. 2014, 55, 4227-4229.
75. Synthesis of 3-Mono-Substituted Binaphthyl-Based Secondary Amine Catalysts via Monobromination of an Axially Chiral Dicarboxylic Acid Derivative
Kano, T.; Takeda, M.; Sakamoto, R.; Maruoka, K.* J. Org. Chem. 2014, 79, 4240-4244.
74. Practical Approach for Asymmetric Hydroxyamination of Aldehydes with in Situ Generated Nitrosocarbonyl Compounds: Application to One-Pot Synthesis of Chiral Allylamines
Kano, T.; Shirozu, F.; Maruoka, K.* Org. Lett. 2014, 16, 1530-1532. (Highlighted in SYNFACTS, 2014, 531)
73. Amine-catalyzed Asymmetric Cross-aldol Reactions Using Hetero-functionalized Acetaldehydes as Nucleophiles
Kano, T.; Sakamoto, R.; Maruoka, K.* Org. Lett. 2014, 16, 944-947.
72. Chiral Brønsted Acid-catalyzed Enantioselective Addition of Indoles to Ketimines
Kano, T.; Takechi, R.; Kobayashi, R.; Maruoka, K.* Org. Biomol. Chem. 2014, 12, 724-727. (Most Downloaded Articles 1位) (Cover Picture)
71. Remote Chirality Control Based on the Organocatalytic Asymmetric Mannich Reaction of α-Thio Acetaldehydes
Kano, T.; Sakamoto, R.; Maruoka, K.* Chem. Commun. 2014, 50, 942-944. (Most Downloaded Articles 5位)
70. Metal-free Enantioselective Hydroxyamination of Aldehydes with Nitrosocarbonyl Compounds Catalyzed by an Axially Chiral Amine
Kano, T.; Shirozu, F.; Maruoka, K.* J. Am. Chem. Soc. 2013, 135, 18036-18039. (Highlighted in SYNFACTS, 2014, 207)
69. Organocatalytic Asymmetric Synthesis of Propargylamines with Two Adjacent Stereocenters: Mannich-Type Reactions of In Situ Generated C-Alkynyl Imines with β-Keto Esters
Kano, T.; Yurino, T.; Maruoka, K.* Angew. Chem., Int. Ed. 2013, 52, 11509-11512. (Highlighted in SYNFACTS, 2013, 1233)
68. Unusual anti-Selective Asymmetric Conjugate Addition of Aldehydes to Nitroalkenes Catalyzed by a Biphenyl-based Chiral Secondary Amine
Kano, T.; Sugimoto, H.; Tokuda, O.; Maruoka, K.* Chem. Commun. 2013, 49, 7028-7030. (Cover Picture)
67. Construction of a Chiral Quaternary Carbon Center by Catalytic Asymmetric Alkylation of 2-Arylcyclohexanones under Phase-transfer Conditions
Kano, T.; Hayashi, Y.; Maruoka, K.* J. Am. Chem. Soc. 2013, 135, 7134-7137. (Most Read articles) (Highlighted in SYNFACTS, 2013, 900) (Highlighted in Org. Process. Res. Dev., 2013, 17, 956)
66. Acid-Catalyzed In Situ Generation of Less Accessible or Unprecedented N-Boc Imines from N-Boc Aminals
Kano, T.; Yurino, T.; Asakawa, D.; Maruoka, K.* Angew. Chem., Int. Ed. 2013, 52, 5532-5534. (Highlighted in SYNFACTS, 2013, 790) (Highlighted in Org. Process. Res. Dev., 2013, 17, 1079)
65. Unique Properties of Chiral Biaryl-based Secondary Amine Catalysts for Asymmetric Enamine Catalysis
Kano, T.; Maruoka, K.* Chem. Sci. 2013, 4, 907-915. (Most Downloaded Articles 3位)
64. One-pot Cross Double-Mannich Reaction of Acetaldehyde Catalyzed by a Binaphthyl-based Amino Sulfonamide
Kano, T.; Sakamoto, R.; Yamaguchi, Y.; Itoh, K.; Maruoka, K.* Chem. Commun. 2013, 49, 1118-1120. (Most Downloaded Articles 2位)
63. Stereoselective Synthesis of Cyclic Amino Acids via Asymmetric Phase-transfer Catalytic Alkylation
Kano, T.; Kumano, T.; Sakamoto, R.; Maruoka, K.* Org. Biomol. Chem. 2013, 11, 271-278. (Most Downloaded Articles 2位) (Cover Picture)
62. Powerful Amino Diol Catalyst for Effecting the Direct Asymmetric Conjugate Addition of Aldehydes to Acrylates
Kano, T.; Shirozu, F.; Akakura, M.; Maruoka, K.* J. Am. Chem. Soc. 2012, 134, 16068-16073. (Highlighted in SYNFACTS, 2012, 1261)
61. Molecular Recognition of Ketomalonates by Asymmetric Aldol Reaction of Aldehydes with Secondary-Amine Organocatalysts
Kano, T.; Song, S.; Maruoka, K.* Chem. Commun. 2012, 48, 7037-7039.
60. Stereocontrolled Synthesis of Vicinal Diamines by Organocatalytic Asymmetric Mannich Reaction of N-Protected Aminoacetaldehydes: Formal Synthesis of (–)-Agelastatin A
Kano, T.; Sakamoto, R.; Akakura, M.; Maruoka, K.* J. Am. Chem. Soc. 2012, 134, 7516-7520. (Most Read articles)
59. Highly Diastereo- and Enantioselective Mannich Reactions of Synthetically Flexible Ketimines with Secondary Amine Organocatalysts
Kano, T.; Song, S.; Kubota, Y.; Maruoka, K.* Angew. Chem., Int. Ed. 2012, 51, 1191-1194.
58. Efficient Organocatalytic Cross-aldol Reaction between Aliphatic Aldehydes through Their Functional Differentiation
Kano, T.; Sugimoto, H.; Maruoka, K.* J. Am. Chem. Soc. 2011, 133, 18130-18133. (Highlighted in SYNFACTS, 2012, 217)
57. The First Example of the Direct Asymmetric Conjugate Addition of Aldehydes to a Methylenemalonate Promoted by an Axially Chiral Amino Diol Catalyst
Kano, T.; Shirozu, F.; Tatsumi, K.; Kubota, Y.; Maruoka, K.* Chem. Sci. 2011, 2311-2313. (Most Downloaded Articles 3位) (Cover Picture)
56. syn-Selective Asymmetric Cross-aldol Reactions between Aldehydes and Glyoxylic Acid Derivatives Catalyzed by an Axially Chiral Amino Sulfonamide
Kano, T.; Noishiki, A.; Sakamoto, R.; Maruoka, K.* Chem. Commun. 2011, 47, 10626-10628.
55. Catalytic Asymmetric Synthesis of Isoxazoline-N-oxides through Conjugate Addition-Cyclization under Phase-transfer Conditions
Kano, T.; Yamamoto, A.; Song, S.; Maruoka, K.* Bull. Chem. Soc. Jpn. 2011, 84, 1057-1065. (Selected Paper)(Top Accessed Articles 6位)
54. Catalytic Asymmetric Synthesis of Isoxazoline-N-oxides under Phase-transfer Conditions
Kano, T.; Yamamoto, A.; Song, S.; Maruoka, K.* Chem. Commun. 2011, 47, 4358-4360. (Cover Picture)
53. Development of Highly Selective Organic Reactions Catalyzed by Designed Amine Organocatalysts
Kano, T.; Maruoka, K.* Bull. Chem. Soc. Jpn. 2010, 83, 1421-1438.
52. Direct Asymmetric Bromination of Aldehydes Catalyzed by a Binaphthyl-based Secondary Amine: Highly Enantio- and Diastereoselective One-pot Synthesis of Bromohydrins
Kano, T.; Shirozu, F.; Maruoka, K.* Chem. Commun. 2010, 46, 7590-7592.
51. Catalytic Asymmetric Synthesis of Cyclic Amino Acids and Alkaloid Derivatives: Application to (+)-Dihydropinidine and Selfotel Synthesis
Kano, T.; Kumano, T.; Sakamoto, R.; Maruoka, K.* Chem. Sci. 2010, 1, 499-501.
50. Metal-Free Direct Asymmetric Aminoxylation of Aldehydes Catalyzed by a Binaphthyl-Based Chiral Amine
Kano, T.; Mii, H.; Maruoka, K.* Angew. Chem., Int. Ed. 2010, 49, 6638-6641. (Highlighted in SYNFACTS, 2010, 1192)
49. Catalytic Asymmetric Synthesis of Cyclic α-Alkyl-amino Acid Derivatives by C,N-Doublealkylation
Kano, T.; Sakamoto, R.; Mii, H.; Maruoka, K.* Tetrahedron 2010, 66, 4900-4904. (Highlighted in SYNFACTS, 2010, 479)
48. Catalytic Asymmetric Synthesis of Cyclic α-Alkyl-amino Acid Derivatives Having a Tetrasubstituted α-Carbon
Wang, Y.-G.; Mii, H.; Kano, T.; Maruoka, K.* Bioorg. Med. Chem. Lett. 2009, 19, 3795-3797.
47. A Designer Axially Chiral Amino Sulfonamide as an Efficient Organocatalyst for Direct Asymmetric anti-Selective Mannich Reactions and syn-Selective Cross-Aldol Reactions
Kano, T.; Yamaguchi, Y.; Maruoka, K.* Chem.–Eur. J. 2009, 15, 6678-6687.
46. Organocatalyzed Direct Asymmetric α-Halogenation of Carbonyl Compounds
Ueda, M.; Kano, T.; Maruoka, K.* Org. Biomol. Chem. 2009, 2005-2012.
45. Enantioselectivity Switch in Direct Asymmetric Aminoxylation Catalyzed by Binaphthyl-Based Chiral Secondary Amines
Kano, T.; Yamamoto, A.; Shirozu, F.; Maruoka, K.* Synthesis 2009, 1557-1563. (Highlighted in SYNFACTS, 2009, 799)
44. Organocatalytic Approach to Enantioselective One-Pot Synthesis of Pyrrolidine, Hexahydropyrrolizine, and Octahydroindolizine Core Structures
Wang, Y.-G.; Kumano, T.; Kano, T.; Maruoka, K.* Org. Lett. 2009, 11, 2027-2029. (Most Read articles) (Highlighted in SYNFACTS, 2009, 678)
43. Rate Enhancement of Phase Transfer Catalyzed Conjugate Additions by CsCl
Kano, T.; Kumano, T.; Maruoka, K.* Org. Lett. 2009, 11, 2023-2025.
42. Direct Asymmetric Benzoyloxylation of Aldehydes Catalyzed by 2-Tritylpyrrolidine
Kano, T.; Mii, H.; Maruoka, K.* J. Am. Chem. Soc. 2009, 131, 3450-3451. (Most Read articles) (Highlighted in SYNFACTS, 2009, 566)
41. A Designer Axially Chiral Amino Sulfonamide as an Efficient Organocatalyst for Direct Asymmetric Mannich Reactions of N-Boc-protected Imines
Kano, T.; Yamaguchi, Y.; Maruoka, K.* Angew. Chem., Int. Ed. 2009, 48, 1838-1840. (Highlighted in SYNFACTS, 2009, 446)
40. Catalytic Enantioselective Construction of All-carbon Quaternary Stereocenters by an Organocatalytic Diels-Alder Reaction of α-Substituted α,β-Unsaturated Aldehydes
Kano, T.; Tanaka, Y.; Osawa, K.; Yurino, T.; Maruoka, K.* Chem. Commun. 2009, 1956-1958. (Cover Picture) (Highlighted in SYNFACTS, 2009, 450)
39. Facile Synthesis of Structurally Diverse 3,3'-Disubstituted 1,1'-Binaphthyl-2,2'-Diamines in Optically Pure Forms
Kano, T.; Tanaka, Y.; Osawa, K.; Yurino, T.; Maruoka, K.* J. Org. Chem. 2008, 73, 7387-7389.
38. Direct Asymmetric Aminoxylation Reaction Catalyzed by a Binaphthyl-based Chiral Amino Sulfonamide with High Catalytic Performance
Kano, T.; Yamamoto, A.; Maruoka, K.* Tetrahedron Lett. 2008, 49, 5369-5371.
37. Direct Asymmetric Iodination of Aldehydes Using an Axially Chiral Bifunctional Amino Alcohol Catalyst
Kano, T.; Ueda, M.; Maruoka, K.* J. Am. Chem. Soc. 2008, 130, 3728-3729. (Highlighted in SYNFACTS, 2008, 643)
36. Direct Asymmetric Aminoxylation Reaction Catalyzed by Axially Chiral Amino Acids
Kano, T.; Yamamoto, A.; Mii, H.; Takai, J.; Shirakawa, S.; Maruoka, K.* Chem. Lett. 2008, 37, 250-251. (Top Accessed Articles)
35. Asymmetric 1,3-Dipolar Cycloadditions of N-Benzyl and N-Diphenylmethyl Nitrones and α,β-Unsaturated Aldehydes Catalyzed by Bis-Titanium Chiral Lewis Acids
Hashimoto, T.; Omote, M.; Hato, Y.; Kano, T.; Maruoka, K.* Chem. Asian J. 2008, 3, 407-412.
34. anti-Selective Direct Asymmetric Mannich Reactions Catalyzed by Chiral Pyrrolidine-based Amino Sulfonamides
Kano, T.; Hato, Y.; Yamamoto, A.; Maruoka, K.* Tetrahedron 2008, 64, 1197-1203.
33. Design of Chiral Bifunctional Secondary Amine Catalysts for Asymmetric Enamine Catalysis
Kano, T.; Maruoka, K.* Chem. Commun. 2008, 5465-5473.
32. Construction of Stereodefined 1,1,2,2-Tetrasubstituted Cyclopropanes by Acid Catalyzed Reaction of Aryldiazoacetates and α-Substituted Acroleins
Hashimoto, T.; Naganawa, Y.; Kano, T.; Maruoka, K.* Chem. Commun. 2007, 5143-5145.
31. Asymmetric 1,3-Dipolar Cycloadditions of Nitrones and Methacrolein Catalyzed by Chiral Bis-Titanium Lewis Acid: A Dramatic Effect of N-Substituent on Nitrone
Hashimoto, T.; Omote, M.; Kano, T.; Maruoka, K.* Org. Lett. 2007, 9, 4805-4808. (Highlighted in SYNFACTS, 2008, 178)
30. exo-Selective Asymmetric Diels-Alder Reaction Catalyzed by Diamine Salts as Organocatalysts
Kano, T.; Tanaka, Y.; Maruoka, K.* Chem. Asian J. 2007, 2, 1161-1165.
29. Asymmetric Organocatalytic Oxy-Michael Addition of Alcohols to α,β-Unsaturated Aldehydes
Kano, T.; Tanaka, Y.; Maruoka, K.* Tetrahedron 2007, 63, 8658-8664.
28. Effects of Aromatic Substituents on Binaphthyl-Based Chiral Spiro-Type Ammonium Salts in Asymmetric Phase-Transfer Reactions
Kano, T.; Lan, Q.; Wang, X.; Maruoka, K.* Adv. Synth. Catal. 2007, 349, 556-560.
27. syn-Selective and Enantioselective Direct Cross-Aldol Reactions between Aldehydes Catalyzed by an Axially Chiral Amino Sulfonamide
Kano, T.; Yamaguchi, Y.; Tanaka, Y.; Maruoka, K.* Angew. Chem., Int. Ed. 2007, 46, 1738-1740. (Highlighted as SYNFACT of the month in SYNFACTS, 2007, 429) (Highlighted in SYNFORM, 2007, A6)
26. Design of Chiral Organocatalysts for Practical Asymmetric Synthesis of Amino Acid Derivatives
Maruoka, K.*; Ooi, T.; Kano, T. Chem. Commun. 2007, 1487-1495. (Top 10 Articles)
25. The Development and Scope of a Versatile Tandem Stille-Oxa-Electrocyclization Reaction
Tambar, U. K.; Kano, T.; Zepernick, J. F.; Stoltz, B. M.* Tetrahedron Lett. 2007, 48, 345-350.
24. Design of a C2-Symmetric Chiral Pyrrolidine-Based Amino Sulfonamide: Application to anti-Selective Direct Asymmetric Mannich Reactions
Kano, T.; Hato, Y.; Maruoka, K.* Tetrahedron Lett. 2006, 47, 8467-8469.
23. Convergent and Diastereoselective Synthesis of the Polycyclic Pyran Core of Saudin
Tambar, U. K.; Kano, T.; Zepernick, J. F.; Stoltz, B. M.* J. Org. Chem. 2006, 71, 8357-8364.
22. Synthesis of a Biphenyl-Based Axially Chiral Amino Acid as a Highly Efficient Catalyst for the Direct Asymmetric Aldol Reaction
Kano, T.; Tokuda, O.; Maruoka, K.* Tetrahedron Lett. 2006, 47, 7423-7426.
21. Design of a Binaphthyl-Based Axially Chiral Amino Acid as an Organocatalyst for Direct Asymmetric Aldol Reactions
Kano, T.; Tokuda, O.; Takai, J.; Maruoka, K.* Chem. Asian J. 2006, 1, 210-215.
20. Highly Efficient Trialkylsilylcyanation of Aldehydes, Ketones and Imines Catalyzed by a Nucleophilic N-Heterocyclic Carbene
Kano, T.; Sasaki, K.; Konishi, T.; Mii, H.; Maruoka, K.* Tetrahedron Lett. 2006, 47, 4615-4618.
19. exo-Selective Asymmetric Diels-Alder Reaction Catalyzed by Diamine Salts as Organocatalysts
Kano, T.; Tanaka, Y.; Maruoka, K.* Org. Lett. 2006, 8, 2687-2689. (Highlighted in SYNFACTS, 2006, 843)
18. Direct Asymmetric Hydroxyamination Reaction Catalyzed by an Axially Chiral Secondary Amine Catalyst
Kano, T.; Ueda, M.; Takai, J.; Maruoka, K.* J. Am. Chem. Soc. 2006, 128, 6046-6047. (Highlighted in SYNFACTS, 2006, 615)
17. Organocatalytic Oxy-Michael Addition of Alcohols to α,β-Unsaturated Aldehydes
Kano, T.; Tanaka, Y.; Maruoka, K.* Tetrahedron Lett. 2006, 47, 3039-3041.
16. Highly Enantioselective Monoalkylation of p-Chlorobenzaldehyde Imine of Glycine tert-Butyl Ester under Mild Phase-Transfer Conditions
Ooi, T.; Arimura, Y.; Hiraiwa, Y.; Yuan, L. M.; Kano, T.; Inoue, T.; Matsumoto, J.; Maruoka, K.* Tetrahedron: Asymmetry 2006, 17, 603-606. (Top-25 most downloaded article) (Highlighted in Org. Process. Res. Dev., 2006, 10, 687)
15. Enantioselective 1,3-Dipolar Cycloaddition Reaction between Diazoacetates and α-Substituted Acroleins: Total Synthesis of Manzacidin A
Kano, T.; Hashimoto, T.; Maruoka, K.* J. Am. Chem. Soc. 2006, 128, 2174-2175. (Highlighted in SYNFACTS, 2006, 645)
14. Design of Chiral Tin(IV) Aryloxide as a Mild Lewis Acid Catalyst for Enantioselective Diels-Alder Reaction
Kano, T.; Konishi, T.; Konishi, S.; Maruoka, K.* Tetrahedron Lett. 2006, 47, 873-875. (Highlighted in SYNFACTS, 2006, 468)
13. anti-Selective Direct Asymmetric Mannich Reactions Catalyzed by Axially Chiral Amino Sulfonamide as an Organocatalyst
Kano, T.; Yamaguchi, Y.; Tokuda, O.; Maruoka, K.* J. Am. Chem. Soc. 2005, 127, 16408-16409. (Highlighted in SYNFACTS, 2006, 74 and Science, 2006, 313, 1584)
12. A Practical Synthesis of (S)-2-Cyclohexyl-2-Phenylglycolic Acid via Organocatalytic Asymmetric Construction of a Tetrasubstituted Carbon Center
Tokuda, O.; Kano, T.; Gao, W.-G.; Ikemoto, T.; Maruoka, K.* Org. Lett. 2005, 7, 5103-5105. (Highlighted in SYNFACTS, 2005, 345)
11. Asymmetric 1,3-Dipolar Cycloaddition Reaction of Nitrones and Acrolein with a Bis-Titanium Catalyst as Chiral Lewis Acid
Kano, T.; Hashimoto, T.; Maruoka, K.* J. Am. Chem. Soc. 2005, 127, 11926-11927. (Highlighted in SYNFACTS, 2005, 321)
10. Progress Toward the Synthesis of Saudin: The Development of a Tandem Stille-Oxa-Electrocylization Reaction
Tambar, U. K.; Kano, T.; Stoltz, B. M.* Org. Lett. 2005, 7, 2413-2416.
9. Design of an Axially Chiral Amino Acid with a Binaphthyl Backbone as an Organocatalyst for a Direct Asymmetric Aldol Reaction
Kano, T.; Takai, J.; Tokuda, O.; Maruoka, K.* Angew. Chem., Int. Ed. 2005, 44, 3055-3057.
8. Enantioselective Acylation of Secondary Alcohols Catalyzed by Chiral N-Heterocyclic Carbenes
Kano, T.; Sasaki, K.; Maruoka, K.* Org. Lett. 2005, 7, 1347-1349.
7. Design of New Polyamine-Based Chiral Phase-Transfer Catalysts for the Enantioselective Synthesis of Phenylalanine
Kano, T.; Konishi, S.; Shirakawa, S.; Maruoka, K.* Tetrahedron: Asymmetry 2004, 15, 1243-1245.
6. Asymmetric Carbon-Carbon Coupling of Phenols or Anilines with Aryllead Triacetates
Kano, T.; Ohyabu, Y.; Saito, S.; Yamamoto, H.* J. Am. Chem. Soc. 2002, 124, 5365-5373.
5. Direct Coupling of Anilines with Aryllead Triacetates
Saito, S.; Kano, T.; Ohyabu, Y.; Yamamoto, H.* Synlett 2000, 1676-1678.
4. Enantioselective Total Synthesis of Nicandrenones
Stoltz, B. M.; Kano, T.; Corey, E. J.* J. Am. Chem. Soc. 2000, 122, 9044-9045.
3. Asymmetric Coupling of Phenols with Arylleads
Saito, S.; Kano, T.; Muto, H.; Nakadai, M.; Yamamoto, H.* J. Am. Chem. Soc. 1999, 121, 8943-8944.
2. Diastereoselective Aldol Reaction with an Acetate Enolate: 2,6-Bis(2-isopropylphenyl)-3,5- dimethylphenol as an Extremely Effective Chiral Auxiliary
Saito, S.; Hatanaka, K.; Kano, T.; Yamamoto, H.* Angew. Chem., Int. Ed. 1998, 37, 3378-3381.
1. 2,6-Bis(2-alkylphenyl)-3,5-dimethylphenol as a New Chiral Phenol with C2-Symmetry. Application to the Asymmetric Alkylation of Aldehydes
Saito, S.; Kano, T.; Hatanaka, K.; Yamamoto, H.* J. Org. Chem. 1997, 62, 5651-5656.