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Welcome to Takiyama Group。

東京農工大学 小金井キャンパス

〒184-8588 東京都小金井市中町2-24-16 BASE本館2階229号室

論文Publication

~2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019, 本、総説はこちら

2019

Kentaro ATSUKAWA, Shoji KUDO, Shuntaro AMARI and Hiroshi TAKIYAMA
Increase of solidification rate to improve quality of productivity for xylitol/sorbitol crystalline candy products
J. Food Eng., in press

Kota TANAKA and Hiroshi TAKIYAMA
Effect of oiling-out during crystallization on purification of an intermediate compound
Org. Process Res. Dev., 2019, 23, 9, 2001-2008
(DOI: 10.1021/acs.oprd.9b00256)

Eriko SATO, Yuichiro SEKI and Hiroshi TAKIYAMA
Control of reaction crystallization of organic compounds using the supersaturation profile
J. Chem. Eng. Jpn., 2019, 52, 7, 599-604
(DOI: 10.1252/jcej.19we017)

Yuko YAMAGUCHI, Woo-Sik KIM and Hiroshi TAKIYAMA
Crystal quality control by using the millimeter-size tube type taylor vortex continuous crystallizer
J. Chem. Eng. Jpn., 2019, 52, 3, 308-310
(DOI: 10.1252/jcej.18we024)

Eriko SATO, Shoji KUDO and Hiroshi TAKIYAMA
Study on control of pH-modulation crystallization utilizing concept of dissociation equilibrium
Chem. Pharm. Bull., 2019, 67, 5, 461-466
(DOI: 10.1248/cpb.c18-01004)

Mitsuki OHYAMA, Shoji KUDO, Shuntaro AMARI and Hiroshi TAKIYAMA
Production of crystalline particles with high homogeneity in reaction crystallization by using pH-solubility-profile
J. Ind. Eng. Chem., 2019, 75, 38-43
(DOI: 10.1016/j.jiec.2019.03.003)

2018

Momoko NISHIMARU, Shoji KUDO and Hiroshi TAKIYAMA
Effect of two kinds of supersaturation on crystal qualities during cocrystallization
J. Chem. Eng. Jpn, 2018, 52, 62, 579-585

Shoji KUDO and Hiroshi TAKIYAMA
Solubility determination for carbamazepine and saccharin in methanol/water mixed solvent: basic data for design of cocrystal production by antisolvent crystallization
J. Chem. Eng. Data, 2018, 63, 451-458
(DOI: 10.1021/acs.jced.7b00920)

Eriko SATO, Yutaka KAMEYAMA, Shoji KUDO and Hiroshi TAKIYAMA
Kinetic study on crystallinity change and degradation process of cefixime trihydrate during drying
J. Chem. Eng. Jpn., 2018, 51, 5, 389-394
(DOI: 10.1252/jcej.17we270)

Shuichi WADA and Hiroshi TAKIYAMA
Proposal of evaluation method for amount of mother liquor in spherical agglomerates
J. Chem. Eng. Jpn., 2018, 51, 3, 269-275
(DOI: 10.1252/jcej.17we043)

Haruka SUZUKI and Hiroshi TAKIYAMA
Investigation of the change in morphology of glycine crystalline particles at the template interface with L-leucine
J. Chem. Eng. Jpn., 2018, 51, 3, 276-281
(DOI: 10.1252/jcej.17we206)

2017

Momoko NISHIMARU, Miku NAKASA, Shoji KUDO and Hiroshi TAKIYAMA
Operation condition for continuous anti-solvent crystallization of CBZ-SAC cocrystal considering deposition risk of undesired crystals
J. Cryst. Growth, 2018, 470C, 89-93
(DOI: 10.1016/j.jcrysgro.2017.04.017)

Shuichi WANDA and Hiroshi TAKIYAMA
Development of simultaneous control of polymorphism and morphology in indomethacin crystallization
J. Cryst. Growth, 2016, 435, 37-41
(DOI: 10.1016/j.jcrysgro.2015.11.038)

Daiki NAGAMATSU, Norihito SATO and Hiroshi TAKIYAMA
Estimation of temperature dependency on crystallization using the critical supersaturation ratio (Sc)
J. Chem. Eng. Jpn., 2017, 50, 8, 66-668
(DOI: 10.1252/jcej.16we274)

2016

Haruka SUZUKI and Hiroshi TAKIYAMA
Observation and evaluation of crystal growth phenomena of glycine at the template interface with L-leucine
Adv. Powder Tech., 2016, 27, 2161-2167
(DOI: 10.1016/j.apt.2016.07.029)

Momoko NISHIMARU, Shoji KUDO and Hiroshi TAKIYAMA
Cocrystal production method reducing deposition risk of undesired single component crystals in anti-solvent cocrystallization
J. Ind. Eng. Chem., 2016, 36, 40-43
(DOI: 10.1016/j.jiec.2016.01.027)

Kazuhiro, TAKEGUCHI, Kazuyoshi OBITSU, Shun HIRASAWA, Ryoki ORII, Shigeru IEDA, Minoru OKADA and Hiroshi TAKIYAMA
Effect of temperature and solvent of solvent-mediated polymorph transformation on ASP3026 polymorphs and scale-up
Org. Process Res. Dev., 2016, 20, 970-976
(DOI: 10.1021/acs.oprd.6b00068)

2015

Shuichi WADA, Jun IIJIMA and Hiroshi TAKIYAMA
Crystallization operation method for recovering Mg resources from the sea water desalination process
J. Ind. Eng. Chem., 2015, 48, 1, 94-98
(DOI: 10.1252/jcej.14we157)

Ai OKUDE and Hiroshi TAKIYAMA
Selective recrystallization of metastable polymorph of melt acetaminophen by using tempering operation
J. Ind. Eng. Chem., 2015, 31, 263-268
(DOI: 10.1016/j.jiec.2015.06.035)

Kazuhiro TAKEGUCHI, Kazuyoshi OBITSU, Shun HIRASAWA, Ryoki ORII, Shigeru IEDA, Minoru OKADA and Hiroshi TAKIYAMA
Strategy for controlling polymorphism of di(arylamino) aryl compound ASP3026 and monitoring solution structures via raman spectroscopy
Org. Process Res. Dev.2015, 19, 1966-1972
(DOI: 10.1021/acs.oprd.5b00208)

Kazuhiro TAKEGUCHI, Yutaka HIRAKURA, Kouji YAMAZAKI, Itsuro SHIMADA, Shigeru IEDA, Minoru OKADA and Hiroshi TAKIYAMA
Characterization and thermodynamic stability of polymorphs of di(arylamino) Aryl compound ASP3026
Chem. Pharm. Bull. 2015, 63, 418-422
(DOI: 10.1248/cpb.c14-00774)

Shoji KUDO, Yutaka SUZAKI Tomomichi HINO, Shinpei KATO and Hiroshi TAKIYAMA
Growth and dissolution kinetics for methacrylic acid crystal in melt
J. Chem. Eng. Jpn., 2015, 48, 11, 922-926
(DOI: 10.1252/jcej.14we388)

Haruka SUZUKI and Hiroshi TAKIYAMA
Templated crystal nucleation phenomena at the air/solution interface focusing on the repulsive force
J. Chem. Eng. Jpn., 2015, 48, 6, 488-490
(DOI: 10.1252/jcej.14we386)

2014

Daiki NAGAMATSU, Yasuo IDA and Hiroshi TAKIYAMA
Evaluation of the difficulty of crystallization of organic compounds using the critical supersaturation ratio (Sc)
J. Cryst. Growth, 2014, 406, 48-52
(DOI: 10.1016/j.jcrysgro.2014.08.012)

Shoji KUDO and Hiroshi TAKIYAMA
Production method of carbamazepine/saccharin cocrystal particles by using two solution mixing based on the ternary phase diagram
J. Cryst. Growth, 2014, 392, 87-91
(DOI: 10.1016/j.jcrysgro.2014.02.003)

2013

Hirokuni YAMAMOTO and Hiroshi TAKIYAMA
Production of organic micro-crystals by using templated crystallization as nucleation trigger
J. Cryst. Growth, 2013, 373, 69-72
(DOI: 10.1016/j.jcrysgro.2012.11.007)

Takuma MINAMISONO and Hiroshi TAKIYAMA
Control of polymorphism in the anti-solvent crystallization with a particular temperature profile
J. Cryst. Growth, 2013, 362, 135-139
(DOI: 10.1016/j.jcrysgro.2011.11.091)

Shoji KUDO, Tomomichi HINO and Hiroshi TAKIYAMA
The effect of morphology of crystals in suspension on scale formation dynamics in cooling crystallization for organic compound
J. Chem. Eng. Jpn., 2013, 46, 11, 790-793
(DOI: 10.1252/jcej.13we140)

Tomomichi HINO, Shinpei KATO and Hiroshi TAKIYAMA
The purity of methacrylic acid crystals under the presence of maleic acid and methanol in melt crystallization
J. Chem. Eng. Jpn., 2013, 46, 11, 785-789
(DOI: 10.1252/jcej.13we132)

Tomomichi HINO, Shinpei KATO and Hiroshi TAKIYAMA
The influence of a small amount of maleic acid on crystal deposition phenomena of methacrylic acid in melt crystallization
J. Cryst. Growth, 2013, 373, 142-145
(DOI: 10.1016/j.jcrysgro.2012.10.016)

2012

Hiroshi TAKIYAMA and Kenji ITO
Production of organic fine-crystalline particles by using the liquid-liquid interface in an emulsion
Chem. Eng. Technol., 2012, 35, 6, 991-994
(DOI: 10.1002/ceat.201200016)

Hiroshi TAKIYAMA
Supersaturation operation for quality control of crystalline particles in solution crystallization
Adv. Powder Technol., 2012, 23, 273-278
(DOI: 10.1016/j.apt.2012.04.009)

Mitsuru SHOJI and Hiroshi TAKIYAMA
The application of two-dimensional population balance model to study the effect of temperature profile on the crystal size distribution and aspect ratio
Cryst. Growth Des., 2012, 12, 5241-5246
(DOI: 10.1021/cg300680f)

Tomomichi HINO, Shinpei KATO and Hiroshi TAKIYAMA
Crystal growth phenomena of methacrylic acid under the presence of maleic acid in melt crystallization
J. Chem. Eng. Jpn., 2012, 45, 10, 868-872
(DOI: 10.1252/jcej.13we132)

Shoji KUDO, Tomomichi HINO and Hiroshi TAKIYAMA
Scale formation dynamics on cooling surface during start-up operation in melt crystallization
J. Chem. Eng. Jpn., 2012, 45, 7, 551-553
(DOI: 10.1252/jcej.11we254)

Shoji KUDO and Hiroshi TAKIYAMA
Production of fine organic crystalline particles by using milli segmented flow crystallizer
J. Chem. Eng. Jpn., 2012, 45, 4, 305-309
(DOI: 10.1252/jcej.11we168)

Takuma MINAMISONO Yoshiaki SATO, Hiroshi ISHIHARA, Takao OMAE, Takashi HASEBE and Hiroshi TAKIYAMA
Solid-state characterization of E3210 polymorphs
J. Chem. Eng. Jpn., 2012, 45, 3, 233-238
(DOI: 10.1252/jcej.11we191)

2011

Mitsuru SHOJI and Hiroshi TAKIYAMA
The influence of crystal orientation on crystal size measurement
J. Chem. Eng. Jpn., 2011, 44, 12, 999-1002
(DOI: 10.1252/jcej.11we190)

Takuma MINAMISONO, Takao OMAE, Takashi KATO and Hiroshi TAKIYAMA
Evaluation of the relative stability of toropane derivative nitrate polymorphs
J. Chem. Eng. Jpn., 2011, 44, 4, 197-207
(DOI: 10.1252/jcej.10we280)

Mitsuru SHOJI and Hiroshi TAKIYAMA
A kinetic study of the influence of modulated undersaturation operation on crystal size distribution in cooling-type batch crystallization
J. Chem. Eng. Jpn., 2011, 44, 3, 191-196
(DOI: 10.1252/jcej.10we251)

Takahiro NISHITA and Hiroshi TAKIYAMA
Influence of admixture impurities on the crystal quality of inorganic phosphorus compound
J. Chem. Eng. Jpn., 2011, 44, 2, 118-122
(DOI: 10.1252/jcej.10we206)

Tomomichi HINO, Shinpei KATO, Yugo Mizokoshi and Hiroshi TAKIYAMA
Solid-liquid equilibrium data for the binary system methacrylic acid + methanol in the high methacrylic acid concentration range
Fluid Phase Equilib., 2011, 312, 14-19
(DOI: 10.1016/j.fluid.2011.09.002)

2010

Hiroshi TAKIYAMA, Takuma MINAMISONO, Yohei OSADA, Masakuni MATSUOKA
Operation design for controlling polymorphism in the anti-solvent crystallization by using ternary phase diagram
Chem. Eng. Res. Des., 2010, 88, 1242-1247
(DOI: 10.1016/j.cherd.2009.09.011)

Takahiro NISHITA and Hiroshi TAKIYAMA
Inhibitory phenomena of crystal growth of inorganic phosphorus compounds by admixture impurities
KAGAKU KOGAKU RONBUNSHU, 2010, 36, 2, 105-110
(DOI: 10.1252/kakoronbunshu.36.105)

2009

Hiroshi TAKIYAMA
A study on modeling and control of salt crystallization under high suspension density conditions

〜2008

Hiroshi TAKIYAMA and Yohei YAMANE
Effects of dissolution water injection methods on CSD in salt crystallization
Bull. Soc. Sea Water Sci., 2008, 62 292-293
(DOI: 10.11457/swsj1965.62.292)

Hirohisa UCHIDA, Atsushi MANAKA, Masakuni MATSUOKA and Hiroshi TAKIAYAMA
Growth phenomena of single crystals of naphthalene in supercritical carbon dioxide
Cryst. Growth Des., 2004, 4, 5, 937-942
(DOI: 10.1021/cg034212u)

Yukiko MARUI, Masakuni MATSUOKA, Hirohisa UCHIDA and Hiroshi TAKIAYAMA
Analysis and simulation of phase transformation kinetics of zeolite a from amorphous phases
J. Chem. Eng. Jpn., 2003, 36, 5, 616-622
(DOI: 10.1252/jcej.36.616)

Yukiko MARUI, Hirohisa UCHIDA, Hiroshi TAKIAYAMA and Masakuni MATSUOKA
Nucleation rates of zeolite a crystals from clear aluminosilicate solutions
J. Chem. Eng. Jpn., 2003, 36, 5, 597-602
(DOI: 10.1252/jcej.36.597)

Hirohisa UCHIDA, Hiroshi TAKIAYAMA and Masakuni MATSUOKA
Molecular dynamics simulation of the solution structure near the solid-liquid interface between the NaCl(100) and NaCl-KCl-H2O solutions
Cryst. Growth Des., 2003, 3, 2, 209-213)
(DOI: 10.1021/cg025513r)

Maiko YAMANOBE, Hiroshi TAKIAYAMA and Masakuni MATSUOKA
FT-IR study on the effect of solvents on polymorphic crystallization of organic compounds
J. Chem. Eng. Jpn., 2002, 35, 6, 569-573)
(DOI: 10.1252/jcej.35.569)

本・総説Books/Review article

滝山 博志
晶析の強化書【増補版】〜有機合成者でもわかる晶析操作と結晶品質の最適化〜


バナースペース

化学システム工学科/化学物理工学科
滝山研究室

〒184-8588
東京都小金井市中町2-24-16
BASE本館2階229号室

htakiyam(@)cc.tuat.ac.jp