Oral presentations at the 77th Annual Meeting of the Society for Biotechnology, Japan
Noriyuki, Satoshi, and Chris gave oral presentations at the 77th Annual Meeting of the Society for Biotechnology, Japan.
Medicinal Enzyme Engineering Laboratory – News
Chris’ first-author paper on ML-based prediction of yeast gene functions published in Life Science Alliance
In collaboration with Professor Araki (Ritsumeikan) and Professors Kondo, Hasunuma, and Ishii (Kobe University), we developed a machine learning method that incorporates MALDI-TOF fingerprint data to improve gene function prediction.
GEnESIS under review at npj Systems Biology and Applications
We propose GEnESIS (Graph-based Enzyme Evolution with Structure-Informed Scoring), a GNN-based workflow for engineering novel enzymes.
DHPAAS structure and mechanism paper published in Nature Communications
With advice from Professor Sode, we discovered new potential oxygen tunnels in DHPAAS. With help from Professor Nakazawa, the first solid-state NMR analysis of mosquito cuticle provided new evidence that the DHPAAS product may form cross-links in insect cuticle.
Satoshi received support from Academist and Sawakami Foundation
Support for developing new Deep Learning methods to create novel enzymes.
Chris received support from Kiban B to develop the ENSO system
Support to develop the Enzyme Selection & Optimization (ENSO) system for engineering diverse new enzymatic reactions; additional support from the G-7 Scholarship Foundation.
Presentations at the 18th Symposium on Biorelevant Chemistry
Noriyuki SHIOURA (B4), Nirannjheeni ALAGAPPAN (B4), Satoshi YUZAWA (B4), and Chris gave presentations at the “18th Symposium on Biorelevant Chemistry”.
Oral presentations at the 76th Annual Meeting of the Japanese Society for Biotechnology
Nirannjheeni ALAGAPPAN (B4) and Chris both gave oral presentations at the 76th Annual Meeting of the Japanese Society for Biotechnology.
Welcome new lab members
Noriyuki SHIOURA (B3), Nirannjheeni ALAGAPPAN (B3), and Satoshi YUZAWA (B3) have joined our lab.
Administrative support
Mrs. Yuko Murakami has joined the lab as administrative assistant.
Oral presentation at the 48th Annual Meeting of the Pesticide Society of Japan
“Machine learning discovery of specialized enzymes for the biosynthesis of aromatic plant compounds.”
New field name established
“The official research field name of "Medicinal Enzyme Engineering" is established at our University.”
Laboratory establishment
“The Medicinal Enzyme Engineering Laboratory (Vavricka Lab) is established at Tokyo University of Agriculture and Technology!.”